The Research Executive Committee is closely involved with the program planning and evaluation activities of the UPCI. Discussions regarding the scientific activities and growth ofthe scientific programs are on the agenda on a regular basis. Similarly, the services provided by UPCI shared facilities, operational efficiencies and the need for new services are also discussed regularly. A formal presentation ofthe research activities ofthe CCSG programs, developing programs and services provided bythe shared facilities are presented to the Scientific Advisory Council (SAC) members of UPCI at the annual SAC meeting, following which SAC's feedback and recommendations are discussed at the quarterly Program Leaders and Shared Facility Directors meeting to get their input. The Research Executive Committee continues to discuss extensively the recommendations provided by SAC and the subsequent comments by the Program Leaders and Shared Facility Directors to take the appropriate steps to enhance the programs and shared facilities. The Annual Scientific Retreat provides an outstanding opportunity for lab based faculty, medical and hematologic oncologists, residents, clinical fellows, postdoctoral fellows (lab based) and graduate students to meet together and share ideas. The 2-day event also provides the opportunity to hear presentations from newly recruited faculty members as well as from established UPCI members who have innovative and important research findings. Funds are being requested for two aspects of UPCI's program planning and evaluation activities. These are funds for annual meetings of UPCI's Scientific Advisory Committee, and the UPCI Annual Scientific Retreat.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA047904-26
Application #
8705427
Study Section
Special Emphasis Panel (ZCA1-RTRB-L)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
26
Fiscal Year
2014
Total Cost
$84,479
Indirect Cost
$28,593
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Chen, Ruochan; Zhu, Shan; Fan, Xue-Gong et al. (2018) High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis. Hepatology 67:1823-1841
Zahorchak, Alan F; Macedo, Camila; Hamm, David E et al. (2018) High PD-L1/CD86 MFI ratio and IL-10 secretion characterize human regulatory dendritic cells generated for clinical testing in organ transplantation. Cell Immunol 323:9-18
Rogers, Meredith C; Lamens, Kristina D; Shafagati, Nazly et al. (2018) CD4+ Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses. J Immunol 201:1253-1266
Butterfield, Lisa H (2018) The Society for Immunotherapy of Cancer Biomarkers Task Force recommendations review. Semin Cancer Biol 52:12-15
Jing, Y; Nguyen, M M; Wang, D et al. (2018) DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor. Oncogene 37:638-650
Singh, Krishna B; Ji, Xinhua; Singh, Shivendra V (2018) Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer. Mol Cancer Ther 17:2079-2090
Gao, Ying; Tan, Jun; Jin, Jingyi et al. (2018) SIRT6 facilitates directional telomere movement upon oxidative damage. Sci Rep 8:5407
Krishnamurthy, Anuradha; Dasari, Arvind; Noonan, Anne M et al. (2018) Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer. Cancer Res 78:5398-5407
Santos, Patricia M; Butterfield, Lisa H (2018) Next Steps for Immune Checkpoints in Hepatocellular Carcinoma. Gastroenterology 155:1684-1686
Liu, Zuqiang; Ge, Yan; Wang, Haiyan et al. (2018) Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2. Nat Commun 9:4682

Showing the most recent 10 out of 1187 publications