Developmental funds provide an essential base of support for the strategic initiatives of the Cancer Center consistent with its overall planning processes. During the current project period this support was applied in three areas: recruitment of new faculty, support of pilot projects and development of shared resources. A total of fifteen new faculty were provided with recruitment support and a significant number of these have subsequently obtained peer-reviewed funding. A total of ten pilot projects were funded over the project period with a significant publication and subsequent funding record. And finally, developmental funds supported three new shared resources which are now being presented as established facilities in this application. Without question, developmental funds have provided an excellent return on investment in all three categories of support. Given the continued growth in the Cancer Center's overall research enterprise and the successful use of developmental funds in the current project period, a new request of $525,000 per year is felt to be justified. This would be allocated as $250,000 per year for new faculty recruitment, $100,000 per year for funding of pilot projects, and $175,000 per year for development of shared resources. The new shared resource facilities that will be developed with the help of these funds include the Viral Vector Core, the Epigenomics Core, and the Cancer Therapeutics and Diagnostic Screening Facility. All three cores will address important needs of the Cancer Center and will complement the function and services of already existing cores.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA060553-18S3
Application #
8486509
Study Section
Subcommittee G - Education (NCI)
Project Start
1997-08-01
Project End
2013-07-31
Budget Start
2012-09-06
Budget End
2013-07-31
Support Year
18
Fiscal Year
2012
Total Cost
$500,019
Indirect Cost
$85,187
Name
Northwestern University at Chicago
Department
Type
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Stack, Trevor; Vahabikashi, Amir; Johnson, Mark et al. (2018) Modulation of Schlemm's canal endothelial cell stiffness via latrunculin loaded block copolymer micelles. J Biomed Mater Res A 106:1771-1779
Blair, Kris M; Mears, Kevin S; Taylor, Jennifer A et al. (2018) The Helicobacter pylori cell shape promoting protein Csd5 interacts with the cell wall, MurF, and the bacterial cytoskeleton. Mol Microbiol 110:114-127
Karabin, Nicholas B; Allen, Sean; Kwon, Ha-Kyung et al. (2018) Sustained micellar delivery via inducible transitions in nanostructure morphology. Nat Commun 9:624
Welch, Whitney A; Spring, Bonnie; Phillips, Siobhan M et al. (2018) Moderating Effects of Weather-Related Factors on a Physical Activity Intervention. Am J Prev Med 54:e83-e89
Kaplan, Nihal; Ventrella, Rosa; Peng, Han et al. (2018) EphA2/Ephrin-A1 Mediate Corneal Epithelial Cell Compartmentalization via ADAM10 Regulation of EGFR Signaling. Invest Ophthalmol Vis Sci 59:393-406
Kenig-Kozlovsky, Yael; Scott, Rizaldy P; Onay, Tuncer et al. (2018) Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels. J Am Soc Nephrol 29:1097-1107
Zhang, Angelica; Veesenmeyer, Jeffrey L; Hauser, Alan R (2018) Phosphatidylinositol 4,5-Bisphosphate-Dependent Oligomerization of the Pseudomonas aeruginosa Cytotoxin ExoU. Infect Immun 86:
Ting, See-Yeun; Bosch, Dustin E; Mangiameli, Sarah M et al. (2018) Bifunctional Immunity Proteins Protect Bacteria against FtsZ-Targeting ADP-Ribosylating Toxins. Cell 175:1380-1392.e14
Nahum-Shani, Inbal; Smith, Shawna N; Spring, Bonnie J et al. (2018) Just-in-Time Adaptive Interventions (JITAIs) in Mobile Health: Key Components and Design Principles for Ongoing Health Behavior Support. Ann Behav Med 52:446-462
Kang, Hong-Jun; Song, Ha Yong; Ahmed, Mohamed A et al. (2018) NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity. Free Radic Biol Med 126:358-371

Showing the most recent 10 out of 1972 publications