Developmental funds are instrumental in supporting faculty recruitment bridge funding, pilot project funding and the establishment of the new Animal Carcinogenesis Core at the University of Hawai'i Cancer Center (UHCC). Achieving the mission and long-term goals UHCC is dependent upon the ability to recruit the highest caliber scientists with clinical, basic, behavioral, epidemiological expertise who can lead high impact investigator initiated research, strengthen research collaborations among members of the Hawai'i Cancer Consortium (HCC), and advance the translational research agenda of UHCC. In the current grant cycle limited CCSG funds were available for use as developmental funds and a majority of the funds were used for strategic recruitments, including the recruitment of Dr. Michele Carbone in 2006, who is now the Director of UHCC. CCSG Developmental Funds were used to support 2 additional recruitments - Dr. Iona Cheng, who is the recipient of a V Foundation award and 2 R01 grants and Dr. Unhee Lim, who was awarded an AICR grant. Bridge funding will provide support for interim salaries and research support for promising investigators. Pilot grants will enable the development of new collaborative initiatives. The newly proposed Animal Carcinogenesis Core will enhance UHCC opportunities to utilize state-of-art animal models for translational cancer research, a murine tumor tissue bank, and expert consultation regarding animal experiments. CCSG developmental funds will ultimately continue to help UHCC leverage significant institutional and philanthropic support, a portion of which has been invested into providing pilot funding and bridge funding to UHCC faculty, many of which have led to new or renewal R01 or equivalent NCI-approved cancer-focused funding. The past success of the CCSG and institutional Developmental Funds reflects the sound leadership of and oversight mechanisms in place to ensure appropriate use.

Public Health Relevance

Developmental funds provide the capital for investment to secure faculty and research resources that translate into innovative discoveries and lead to scientific agendas that advance the mission of UHCC to reduce the burden of cancer among people in Hawai'i.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA071789-14S2
Application #
8724392
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
14
Fiscal Year
2013
Total Cost
$4,213
Indirect Cost
$1,423
Name
University of Hawaii
Department
Type
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Gu, Yuanzhuo; Wei, Xiyang; Sun, Yulin et al. (2018) miR-192-5p silencing by genetic aberrations is a key event in hepatocellular carcinomas with cancer stem cell features. Cancer Res :
Lim, Unhee; Monroe, Kristine R; Buchthal, Steve et al. (2018) Propensity for Intra-abdominal and Hepatic Adiposity Varies Among Ethnic Groups. Gastroenterology :
Maskarinec, Gertraud; Ju, Dan; Fong, Jaimie et al. (2018) Mammographic density and breast tissue expression of inflammatory markers, growth factors, and vimentin. BMC Cancer 18:1191
Amshoff, Yvette; Maskarinec, Gertraud; Shvetsov, Yurii B et al. (2018) Type 2 diabetes and colorectal cancer survival: The multiethnic cohort. Int J Cancer 143:263-268
Maskarinec, Gertraud; Jacobs, Simone; Amshoff, Yvette et al. (2018) Sleep duration and incidence of type 2 diabetes: the Multiethnic Cohort. Sleep Health 4:27-32
Conroy, Shannon M; Shariff-Marco, Salma; Yang, Juan et al. (2018) Characterizing the neighborhood obesogenic environment in the Multiethnic Cohort: a multi-level infrastructure for cancer health disparities research. Cancer Causes Control 29:167-183
Shimizu, Yoshiko; Furuya, Hideki; Tamashiro, Paulette M et al. (2018) Genetic deletion of sphingosine kinase 1 suppresses mouse breast tumor development in an HER2 transgenic model. Carcinogenesis 39:47-55
Aumueller, Nicole; Boushey, Carol J; Franke, Adrian A et al. (2018) Diet quality measured by four a priori-defined diet quality indices is associated with lipid-soluble micronutrients in the Multiethnic Cohort Study (MEC). Eur J Clin Nutr :
Huang, Brian Z; Le Marchand, Loic; Haiman, Christopher A et al. (2018) Atopic allergic conditions and pancreatic cancer risk: Results from the Multiethnic Cohort Study. Int J Cancer 142:2019-2027
Jenkins, Mark A; Win, Aung Ko; Templeton, Allyson S et al. (2018) Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC). Int J Epidemiol 47:387-388i

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