Bioinformatics is playing an increasingly important role in cancer research extending from basic evaluation of cancer genetics through translational and clinical research. It is also playing an important role in connecting fields of cancer research that were previously thought to be separate, and to assisting other shared resources in sharing and utilizing large volumes of data. The mission of the HCCC Bioinformatics Shared Resource is to support the informatics needs of the clinical, basic and population scientists of the HCCC. This shared resource has the expertise to collect and utilize large-scale data sets, including molecular assays, is available to all HCCC members. Such uses are rarely a simple matter of deploying an existing software tool by the end user, thus the staff of this shared resource will assist investigators throughout the phases of experiment design and collaborate with the investigator and other shared research resources such as the DNA core and Biostatistics Core in data analysis and interpretation. Bioinformatics Shared Resource staff have the expertise to develop software tools de novo or to adapt existing tools to custom settings.
Bioinformatics is increasingly important in cancer research and is having significant impact on basic, clinical,and population-based research as large amounts of data become available. The Bioinformatics Core also plays a central role in serving the needs of the other shared resources of the HCCC.
|Meyerholz, David K; Ofori-Amanfo, Georgina K; Leidinger, Mariah R et al. (2017) Immunohistochemical Markers for Prospective Studies in Neurofibromatosis-1 Porcine Models. J Histochem Cytochem 65:607-618|
|Ebbert, Jon O; Little, Melissa A; Klesges, Robert C et al. (2017) Step Care treatment for smoking cessation. Health Educ Res 32:1-11|
|Sfeir, J G; Drake, M T; LaPlant, B R et al. (2017) Validation of a vitamin D replacement strategy in vitamin D-insufficient patients with lymphoma or chronic lymphocytic leukemia. Blood Cancer J 7:e526|
|Mohiuddin, I; Allen, B G (2017) A Single-Institution Experience in Treating Thymic Carcinoma. Int J Radiat Oncol Biol Phys 98:229|
|Miller, Benjamin J (2017) CORR Insights®: Is It Appropriate to Treat Sarcoma Metastases With Intramedullary Nailing? Clin Orthop Relat Res 475:218-220|
|Huang, Jianguo; Chen, Mark; Whitley, Melodi Javid et al. (2017) Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma. Nat Commun 8:15999|
|Jethava, Yogesh S; Barlogie, Bart; Tricot, Guido J (2017) Drug Combinations with Transplantation for Myeloma. N Engl J Med 377:91-2|
|Gilbertson-White, Stephanie; Bohr, Nicole; Wickersham, Karen E (2017) Conducting Biobehavioral Research in Patients With Advanced Cancer: Recruitment Challenges and Solutions. Biol Res Nurs 19:481-490|
|Rogers, Laura M; Mott, Sarah L; Smith, Brian J et al. (2017) Complement-Regulatory Proteins CFHR1 and CFHR3 and Patient Response to Anti-CD20 Monoclonal Antibody Therapy. Clin Cancer Res 23:954-961|
|Eppsteiner, Robert W; Fowlkes, Jonathan W; Anderson, Carryn M et al. (2017) Aggressive Salivary Malignancies at Early Stage: Outcomes and Implications for Treatment. Ann Otol Rhinol Laryngol 126:525-529|
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