CCSG Developmental Funds are critical to the continued growth and development of the Winship Cancer Institute (Winship). These funds provide a critical base of funding enabling Winship to advance its strategic plan by investing in the cancer center's highest priorities. Winship's initial type 1 CCSG award Included approximately $800,000 of Development Funds over three years, and these funds have supported Winship's pilot grant program and two developing shared resources, Bioinfonnatics and Transgenic Mouse Facility. Since April 2009, Winship has distributed 24 pilot grants directly linked to CCSG developmental funds. In addition, the Winship has allocated over $1 million in philanthropic funds for matching pilot grants during the same time period. In total, Winship has distributed over $1.4 million in pilot grant funding to its members to accelerate progress within their research programs, in this current application, Winship is requesting $437,818 in developmental funds per year primarily to continue its pilot grant program and to advance Winship's strategic initiatives through faculty recruitment. This would be allocated as $200,000/year for faculty recruitment in defined domains as identified by the Winship Strategic Plan 2010-2015. Another $200,000/year would continue to support the Winship Pilot Grant Program, with a particular focus on awards that Involve: 1. New Investigations in partnership with the Emory Chemical Biology Center;2. New initiatives in comparative effectiveness research In oncology;3. Research projects in conjunction with an NCI-supported cancer cooperative group or network;4. Research partnerships with investigators from another NCI-designated cancer center;or 5. Investigations in partnership with faculty from another research institution in Georgia. The current request for Developmental Funds in combination with the continued commitment of institutional funds will allow the Executive Director and his leadership team to continue the planned development in a number of strategic recruitments and research development. This support will enable Winship to move toward fulfilling its vision of being a transformative leader in the integration of cancer research, education, and care.

Public Health Relevance

The requested Developmental Funds will provide additional support for the continued growth and development by sponsoring faculty recruitment and pilot grants for the members of the Winship Cancer Institute.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA138292-05S2
Application #
8710545
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
5
Fiscal Year
2013
Total Cost
$2,340
Indirect Cost
$657
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Havel, L S; Kline, E R; Salgueiro, A M et al. (2015) Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to control focal adhesion kinase activity. Oncogene 34:1979-90
Forghani, Parvin; Khorramizadeh, Mohammad R; Waller, Edmund K (2014) Silibinin inhibits accumulation of myeloid-derived suppressor cells and tumor growth of murine breast cancer. Cancer Med 3:215-24
Smith, Alicia K; Conneely, Karen N; Pace, Thaddeus W W et al. (2014) Epigenetic changes associated with inflammation in breast cancer patients treated with chemotherapy. Brain Behav Immun 38:227-36
Ha, Shin-Woo; Weitzmann, M Neale; Beck Jr, George R (2014) Bioactive silica nanoparticles promote osteoblast differentiation through stimulation of autophagy and direct association with LC3 and p62. ACS Nano 8:5898-910
Nooka, Ajay K; Johnson, Heather R; Kaufman, Jonathan L et al. (2014) Pharmacoeconomic analysis of palifermin to prevent mucositis among patients undergoing autologous hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 20:852-7
Capaldo, Christopher T; Farkas, Attila E; Hilgarth, Roland S et al. (2014) Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins. Mol Biol Cell 25:2710-9
Sullivan, Harold C; Oprea-Ilies, Gabriela; Adams, Amy L et al. (2014) Triple-negative breast carcinoma in African American and Caucasian women: clinicopathology, immunomarkers, and outcome. Appl Immunohistochem Mol Morphol 22:17-23
Brodie, Seth A; Li, Ge; El-Kommos, Adam et al. (2014) Class I HDACs are mediators of smoke carcinogen-induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer. Cancer Prev Res (Phila) 7:351-61
Wang, Hongyan; Wang, Ya (2014) Heavier ions with a different linear energy transfer spectrum kill more cells due to similar interference with the Ku-dependent DNA repair pathway. Radiat Res 182:458-61
Jurchenko, Carol; Chang, Yuan; Narui, Yoshie et al. (2014) Integrin-generated forces lead to streptavidin-biotin unbinding in cellular adhesions. Biophys J 106:1436-46

Showing the most recent 10 out of 49 publications