The Cancer Center Biostatistics Shared Resource (BSR) functions as a centralized biostatistics and informatics support core and brings together expertise and intellectual resources campus-wide in biostatistics, clinical trials, bioinformatics, statistical genetics, epidemiology, and data management for all the Cancer Center investigators. BSR provides Cancer Center members with access to comprehensive biostatistics and bioinformatics expertise to ensure the statistical integrity, to optimize the experimental design and data analysis, and to extract and illuminate all relevant scientific and clinical information from the data. BSR biostatisticians play important integrated roles in each of the Cancer Center Scientific Programs and Disease Oriented Teams. Their significant contributions are reflected in both obtaining and sustaining major collaborative extramural research grants (SPORE, Center Grants, ROI's, and American Cancer Society grants) and publishing high-impact journal articles. These collaborations include: (1) As equal collaborators, BSR biostatisticians work on a large number of research projects of the Cancer Center's Scientific Programs and Disease Oriented Teams;(2) BSR biostatisticians serve as statistical reviewers on Cancer Center major committees (PRMC, DSMC, Clinical Cancer Research Committee and Pilot Awards Committee). (3) BSR biostatisticians provide education and training opportunities to clinical scholars and junior investigators through lectures and seminars;(4) BSR biostatisticians conduct statistical methodological research emerging from collaborative cancer research. In addition, BSR biostatisticians are also available for short term assistance on statistical analyses for Cancer Center members. The services of the Shared Resource are integrated with those of the Department of Clinical Sciences and NIH-funded Clinical and Translational Sciences Award (CTSA) to assure access to specialized expertise such as statistical genetics. Assistance is available on all types of research projects, ranging from clinical trials, basic science experiments, to epidemiological studies.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA142543-05
Application #
8711040
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
5
Fiscal Year
2014
Total Cost
$120,862
Indirect Cost
$1,855
Name
University of Texas Sw Medical Center Dallas
Department
Type
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Huang, Xiumei; Motea, Edward A; Moore, Zachary R et al. (2016) Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors. Cancer Cell 30:940-952
Singal, Amit G; Gupta, Samir; Tiro, Jasmin A et al. (2016) Outreach invitations for FIT and colonoscopy improve colorectal cancer screening rates: A randomized controlled trial in a safety-net health system. Cancer 122:456-63
Knudsen, Erik S; O'Reilly, Eileen M; Brody, Jonathan R et al. (2016) Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine. Gastroenterology 150:48-63
Gallardo-Montejano, Violeta I; Saxena, Geetu; Kusminski, Christine M et al. (2016) Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function. Nat Commun 7:12723
Skinner, Celette Sugg; Gupta, Samir; Halm, Ethan A et al. (2016) Development of the Parkland-UT Southwestern Colonoscopy Reporting System (CoRS) for evidence-based colon cancer surveillance recommendations. J Am Med Inform Assoc 23:402-6
McNamara, Ryan P; Reeder, Jonathan E; McMillan, Elizabeth A et al. (2016) KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II. Mol Cell 61:39-53
Belfatto, Antonella; White, Derek A; Mason, Ralph P et al. (2016) Tumor radio-sensitivity assessment by means of volume data and magnetic resonance indices measured on prostate tumor bearing rats. Med Phys 43:1275-84
Wylie, Annika; Jones, Amanda E; D'Brot, Alejandro et al. (2016) p53 genes function to restrain mobile elements. Genes Dev 30:64-77
Fernando, W Shirangi; Martins, André F; Zhao, Piyu et al. (2016) Breaking the Barrier to Slow Water Exchange Rates for Optimal Magnetic Resonance Detection of paraCEST Agents. Inorg Chem 55:3007-14
Singal, Amit G; Tiro, Jasmin A; Marrero, Jorge A et al. (2016) Mailed Outreach Program Increases Ultrasound Screening of Patients with Cirrhosis for Hepatocellular Carcinoma. Gastroenterology :

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