The Cancer Center Biostatistics Shared Resource (BSR) functions as a centralized biostatistics and informatics support core and brings together expertise and intellectual resources campus-wide in biostatistics, clinical trials, bioinformatics, statistical genetics, epidemiology, and data management for all the Cancer Center investigators. BSR provides Cancer Center members with access to comprehensive biostatistics and bioinformatics expertise to ensure the statistical integrity, to optimize the experimental design and data analysis, and to extract and illuminate all relevant scientific and clinical information from the data. BSR biostatisticians play important integrated roles in each of the Cancer Center Scientific Programs and Disease Oriented Teams. Their significant contributions are reflected in both obtaining and sustaining major collaborative extramural research grants (SPORE, Center Grants, ROI's, and American Cancer Society grants) and publishing high-impact journal articles. These collaborations include: (1) As equal collaborators, BSR biostatisticians work on a large number of research projects of the Cancer Center's Scientific Programs and Disease Oriented Teams;(2) BSR biostatisticians serve as statistical reviewers on Cancer Center major committees (PRMC, DSMC, Clinical Cancer Research Committee and Pilot Awards Committee). (3) BSR biostatisticians provide education and training opportunities to clinical scholars and junior investigators through lectures and seminars;(4) BSR biostatisticians conduct statistical methodological research emerging from collaborative cancer research. In addition, BSR biostatisticians are also available for short term assistance on statistical analyses for Cancer Center members. The services of the Shared Resource are integrated with those of the Department of Clinical Sciences and NIH-funded Clinical and Translational Sciences Award (CTSA) to assure access to specialized expertise such as statistical genetics. Assistance is available on all types of research projects, ranging from clinical trials, basic science experiments, to epidemiological studies.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA142543-05
Application #
8711040
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
5
Fiscal Year
2014
Total Cost
$120,862
Indirect Cost
$1,855
Name
University of Texas Sw Medical Center Dallas
Department
Type
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Rutkowski, Joseph M; Pastor, Johanne; Sun, Kai et al. (2017) Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression. Kidney Int 91:324-337
Eskiocak, Banu; McMillan, Elizabeth A; Mendiratta, Saurabh et al. (2017) Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma. Cancer Discov 7:832-851
Singh, Jaspal; Rustagi, Vineeta; Zhang, Shanrong et al. (2017) On-bead combinatorial synthesis and imaging of europium(III)-based paraCEST agents aids in identification of chemical features that enhance CEST sensitivity. Magn Reson Chem 55:747-753
Singh, Dinesh K; Kollipara, Rahul K; Vemireddy, Vamsidara et al. (2017) Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma. Cell Rep 18:961-976
Gu, Yi-Feng; Cohn, Shannon; Christie, Alana et al. (2017) Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade. Cancer Discov 7:900-917
Lee, Ming Y; Sumpter Jr, Rhea; Zou, Zhongju et al. (2017) Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep 18:48-60
Gao, Boning; Huang, Chunxian; Kernstine, Kemp et al. (2017) Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions. Oncotarget 8:11114-11126
Howard, James J; Sturge, Carolyn R; Moustafa, Dina A et al. (2017) Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers. Antimicrob Agents Chemother 61:
Skinner, Celette Sugg; Ahn, Chul; Halm, Ethan A et al. (2017) Recommendation of colorectal cancer testing among primary care patients younger than 50 with elevated risk. Prev Med 102:20-23
Garcia, Sandra; Bisen, Ajit; Yan, Jingsheng et al. (2017) Thoracic Oncology Clinical Trial Eligibility Criteria and Requirements Continue to Increase in Number and Complexity. J Thorac Oncol 12:1489-1495

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