The overall aim of this Core Center of Excellence (CCOE) is to conduct research that will transform etiological models of drug abuse and sexual risk behavior and the prevention programs they inform in general and those for rural African American children, youth, and their families in particular. The need for this transformation is documented by inclusive reviews of drug abuse and sexual risk behavior prevention efforts that reveal mixed and inconsistent results. This inconsistent impact is a major concern that indicates a need for new approaches to etiologic models of drug abuse and sexual risk behavior, particularly greater articulation of the ways in which the interface among genetic, psychosocial, and developmental processes can be used to transform them. To reach this goal we have assembled a team of senior and early career investigators with a successful history of collaboration who have backgrounds in molecular and statistical genetics, genetic epidemiology, public health, human development, and prevention science. This network of investigators will access the Shared Resources Core, a unique combination of data sets, genetic laboratory and specimen repository resources, statistical and bioinformatic services, and data collection and program implementation teams. Data from seven core projects were collected from more than 6,000 African American individuals, approximately 5,000 (83%) of whom live in small towns and rural communities. These data include (a) longitudinal assessments of drug use and abuse and sexual risk behavior phenotypes;(b) genetic data;(c) developmentally appropriate assessments of self-regulatory processes;and (d) multilevel assessments of individual characteristics, social adaptation, parenting/family processes, and neighborhood/community contexts. The organizational and administrative structure of the CCOE will organize and prioritize CCOE scientists'research efforts, providing an integrated process for translating findings into transformations of etiologic models of drug abuse and sexual risk behavior that increase their predictive utility and the efficacy of the prevention progress they inform.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZDA1-EXL-T (02))
Program Officer
Crump, Aria
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Georgia
Organized Research Units
United States
Zip Code
Levine, Cynthia S; Basu, Devika; Chen, Edith (2017) Just World Beliefs Are Associated With Lower Levels of Metabolic Risk and Inflammation and Better Sleep After an Unfair Event. J Pers 85:232-243
Zapolski, Tamika C B; Banks, Devin E; Lau, Katherine S L et al. (2017) Perceived Police Injustice, Moral Disengagement, and Aggression Among Juvenile Offenders: Utilizing the General Strain Theory Model. Child Psychiatry Hum Dev :
Kogan, Steven M; Cho, Junhan; Brody, Gene H et al. (2017) Pathways linking marijuana use to substance use problems among emerging adults: A prospective analysis of young Black men. Addict Behav 72:86-92
Brody, Gene H; Yu, Tianyi; Chen, Edith et al. (2017) Family-centered prevention ameliorates the association between adverse childhood experiences and prediabetes status in young black adults. Prev Med 100:117-122
Windle, Michael; Windle, Rebecca C (2017) The Measurement of Adolescent Alcohol Problems via Item Response Theory and Their 15-Year Prospective Associations with Alcohol and Other Psychiatric Disorders. Alcohol Clin Exp Res 41:399-406
Amlung, Michael; Vedelago, Lana; Acker, John et al. (2017) Steep delay discounting and addictive behavior: a meta-analysis of continuous associations. Addiction 112:51-62
Hostinar, Camelia E; Davidson, Richard J; Graham, Eileen K et al. (2017) Frontal brain asymmetry, childhood maltreatment, and low-grade inflammation at midlife. Psychoneuroendocrinology 75:152-163
Kogan, Steven M; Cho, Junhan; Oshri, Assaf et al. (2017) The influence of substance use on depressive symptoms among young adult black men: The sensitizing effect of early adversity. Am J Addict 26:400-406
Davis, Molly; Thomassin, Kristel; Bilms, Joanie et al. (2017) Preschoolers' genetic, physiological, and behavioral sensitivity factors moderate links between parenting stress and child internalizing, externalizing, and sleep problems. Dev Psychobiol 59:473-485
Barton, Allen W; Beach, Steven R H; Lavner, Justin A et al. (2017) Is Communication a Mechanism of Relationship Education Effects among Rural African Americans? J Marriage Fam 79:1450-1461

Showing the most recent 10 out of 220 publications