Health and economic consequences of substance abuse. Substance use is a significant public health issue in the U.S. Over 57.8 million Americans aged 12 or older binge drink and 19.9 million individuals aged 12 or older use illicit drugs. Nearly one-fourth of Americans smoke cigarettes, and cigarette smoking remains the leading preventable cause of morbidity and mortality in the U.S(2) Over 22.3 million Americans meet criteria for a SUD Substance use among youth also remains a major public health problem. According to the schoolbased. Monitoring the Future study , almost half (47%) of all 12 graders have tried an illicit drug in their lifetime. Cannabis is the most prevalent illicit psychoactive substance used by adolescents in the U.S.(2) with 43% of 12th graders reporting marijuana use. Additionally, 72% of youth in this age group have used alcohol, and over 55% have been drunk. Approximately 45% of this group has used cigarettes. Further, rates of nonmedical use of prescripfion opioids among youth have markedly increased in the recent past (e.g., 1 in ten 12th graders report non-medical use of Vicodin in the past year)(3). Substance use results in numerous, significant social, medical, psychological, and economic consequences and is associated with marked productivity losses, criminality, and health care costs, including illness and infectious diseases, such as HIV and hepatifis. Approximately one in five deaths in the U.S. (more than one-half million persons each year) is a result of substance use(4). Recent esfimates indicate that the cost of SUDs in the U.S. is over one-half trillion dollars(5).

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Borodovsky, Jacob T; Budney, Alan J (2018) Cannabis regulatory science: risk-benefit considerations for mental disorders. Int Rev Psychiatry 30:183-202
Knapp, Ashley A; Lee, Dustin C; Borodovsky, Jacob T et al. (2018) Emerging Trends in Cannabis Administration Among Adolescent Cannabis Users. J Adolesc Health :
Quanbeck, Andrew; Gustafson, David H; Marsch, Lisa A et al. (2018) Implementing a Mobile Health System to Integrate the Treatment of Addiction Into Primary Care: A Hybrid Implementation-Effectiveness Study. J Med Internet Res 20:e37
Guarino, Honoria; Fong, Chunki; Marsch, Lisa A et al. (2018) Web-Based Cognitive Behavior Therapy for Chronic Pain Patients with Aberrant Drug-Related Behavior: Outcomes from a Randomized Controlled Trial. Pain Med 19:2423-2437
Eisenberg, Ian W; Bissett, Patrick G; Canning, Jessica R et al. (2018) Applying novel technologies and methods to inform the ontology of self-regulation. Behav Res Ther 101:46-57
Beckham, Jean C; Adkisson, Kelsie A; Hertzberg, Jeffrey et al. (2018) Mobile contingency management as an adjunctive treatment for co-morbid cannabis use disorder and cigarette smoking. Addict Behav 79:86-92
Stoianova, Maria; Tampke, Elizabeth C; Lansing, Amy Hughes et al. (2018) Delay discounting associated with challenges to treatment adherence and glycemic control in young adults with type 1 diabetes. Behav Processes 157:474-477
Duncan, Lindsay R; Hieftje, Kimberly D; Pendergrass, Tyra M et al. (2018) Preliminary investigation of a videogame prototype for cigarette and marijuana prevention in adolescents. Subst Abus :1-5
Aschbrenner, Kelly A; Patten, Christi A; Brunette, Mary F (2018) Feasibility of a support person intervention to promote smoking cessation treatment use among smokers with mental illness. Transl Behav Med 8:785-792
Borodovsky, Jacob T; Levy, Sharon; Fishman, Marc et al. (2018) Buprenorphine Treatment for Adolescents and Young Adults With Opioid Use Disorders: A Narrative Review. J Addict Med 12:170-183

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