Health and economic consequences of substance abuse. Substance use is a significant public health issue in the U.S. Over 57.8 million Americans aged 12 or older binge drink and 19.9 million individuals aged 12 or older use illicit drugs. Nearly one-fourth of Americans smoke cigarettes, and cigarette smoking remains the leading preventable cause of morbidity and mortality in the U.S(2) Over 22.3 million Americans meet criteria for a SUD Substance use among youth also remains a major public health problem. According to the schoolbased. Monitoring the Future study , almost half (47%) of all 12 graders have tried an illicit drug in their lifetime. Cannabis is the most prevalent illicit psychoactive substance used by adolescents in the U.S.(2) with 43% of 12th graders reporting marijuana use. Additionally, 72% of youth in this age group have used alcohol, and over 55% have been drunk. Approximately 45% of this group has used cigarettes. Further, rates of nonmedical use of prescripfion opioids among youth have markedly increased in the recent past (e.g., 1 in ten 12th graders report non-medical use of Vicodin in the past year)(3). Substance use results in numerous, significant social, medical, psychological, and economic consequences and is associated with marked productivity losses, criminality, and health care costs, including illness and infectious diseases, such as HIV and hepatifis. Approximately one in five deaths in the U.S. (more than one-half million persons each year) is a result of substance use(4). Recent esfimates indicate that the cost of SUDs in the U.S. is over one-half trillion dollars(5).

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Aronson, Ian David; Marsch, Lisa A; Rajan, Sonali et al. (2015) Computer-based video to increase HIV testing among emergency department patients who decline. AIDS Behav 19:516-22
Hieftje, Kimberly; Duncan, Lindsay R; Fiellin, Lynn E (2014) Novel methods to collect meaningful data from adolescents for the development of health interventions. Health Promot Pract 15:714-22
Chaple, Michael; Sacks, Stanley; McKendrick, Karen et al. (2014) Feasibility of a computerized intervention for offenders with substance use disorders: a research note. J Exp Criminol 10:105-127
Ben-Zeev, Dror; Brenner, Christopher J; Begale, Mark et al. (2014) Feasibility, acceptability, and preliminary efficacy of a smartphone intervention for schizophrenia. Schizophr Bull 40:1244-53
Berman, Margit I; Buckey Jr, Jay C; Hull, Jay G et al. (2014) Feasibility study of an interactive multimedia electronic problem solving treatment program for depression: a preliminary uncontrolled trial. Behav Ther 45:358-75
Marsch, Lisa A; Guarino, Honoria; Acosta, Michelle et al. (2014) Web-based behavioral treatment for substance use disorders as a partial replacement of standard methadone maintenance treatment. J Subst Abuse Treat 46:43-51
Meredith, Steven E; Robinson, Andrew; Erb, Philip et al. (2014) A mobile-phone-based breath carbon monoxide meter to detect cigarette smoking. Nicotine Tob Res 16:766-73
Ramsey, Alex; Lord, Sarah; Torrey, John et al. (2014) Paving the Way to Successful Implementation: Identifying Key Barriers to Use of Technology-Based Therapeutic Tools for Behavioral Health Care. J Behav Health Serv Res :
Marsch, Lisa A; Carroll, Kathleen M; Kiluk, Brian D (2014) Technology-based interventions for the treatment and recovery management of substance use disorders: a JSAT special issue. J Subst Abuse Treat 46:1-4
Marsch, Lisa A; Gustafson, David H (2013) The Role of Technology in Health Care Innovation: A Commentary. J Dual Diagn 9:101-103

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