A rate-limiting step for many studies of the nervous system is obtaining and effectively using the sophisticated technical hardware and analytical methods needed for innovative research. These constraints apply as well to studies of neural signal processing in the brain as they do to studies of disordered processing in animal models of hearing or balance deficits. Even if hardware/software systems are available for planned experiments, they inevitably require modification for special purposes or integration with other systems in the laboratory. This Engineering Core aims to solve these electronics and computer problems by providing computer programming and electronics expertise to researchers in the Center for Hearing and Balance. The cumulative expertise of our staff makes it possible for our research faculty to focus on experiments and not technology development and allows rapid progress in the use of new technologies. During the past five years this core has developed new behavioral interfaces, new telemetric recording equipment for use in awake and unrestrained animals, and new software for on-line optimization of neuron models. We have adapted multi-single unit recording techniques for our uses and have provided support for routine problems of technology usage.

National Institute of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
Center Core Grants (P30)
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Special Emphasis Panel (ZDC1-SRB-L)
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Johns Hopkins University
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Ward, Bryan K; Roberts, Dale C; Della Santina, Charles C et al. (2014) Magnetic vestibular stimulation in subjects with unilateral labyrinthine disorders. Front Neurol 5:28
Ropp, Tessa-Jonne F; Tiedemann, Kerrie L; Young, Eric D et al. (2014) Effects of unilateral acoustic trauma on tinnitus-related spontaneous activity in the inferior colliculus. J Assoc Res Otolaryngol 15:1007-22
Slee, Sean J; Young, Eric D (2014) Alignment of sound localization cues in the nucleus of the brachium of the inferior colliculus. J Neurophysiol 111:2624-33
Fuchs, Paul Albert (2014) A 'calcium capacitor' shapes cholinergic inhibition of cochlear hair cells. J Physiol 592:3393-401
May, Bradford J; Bowditch, Stephen; Liu, Yinda et al. (2014) Mitigation of informational masking in individuals with single-sided deafness by integrated bone conduction hearing aids. Ear Hear 35:41-8
Weisz, Catherine J C; Glowatzki, Elisabeth; Fuchs, Paul Albert (2014) Excitability of type II cochlear afferents. J Neurosci 34:2365-73
Benito-Gonzalez, Ana; Doetzlhofer, Angelika (2014) Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling. J Neurosci 34:12865-76
Ward, Bryan K; Tan, Grace X-J; Roberts, Dale C et al. (2014) Strong static magnetic fields elicit swimming behaviors consistent with direct vestibular stimulation in adult zebrafish. PLoS One 9:e92109
Fuchs, Paul Albert; Lehar, Mohamed; Hiel, Hakim (2014) Ultrastructure of cisternal synapses on outer hair cells of the mouse cochlea. J Comp Neurol 522:717-29
Ronderos, David S; Lin, Chun-Chieh; Potter, Christopher J et al. (2014) Farnesol-detecting olfactory neurons in Drosophila. J Neurosci 34:3959-68

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