The objective of the Functional Genomics Core is to provide state of the art experiment planning, sample preparation, quality assessment, microarray, DNA sequencing, and data analysis services to DRC members.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK019525-36
Application #
8310455
Study Section
Special Emphasis Panel (ZDK1-GRB-S (J1))
Project Start
Project End
Budget Start
2012-05-15
Budget End
2013-03-31
Support Year
36
Fiscal Year
2012
Total Cost
$174,645
Indirect Cost
$65,492
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Brown, Justin C; Troxel, Andrea B; Ky, Bonnie et al. (2016) A randomized phase II dose-response exercise trial among colon cancer survivors: Purpose, study design, methods, and recruitment results. Contemp Clin Trials 47:366-75
Zhang, Yuxiang; Fang, Bin; Damle, Manashree et al. (2016) HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms. Genes Dev 30:1636-44
Titchenell, Paul M; Quinn, William J; Lu, Mingjian et al. (2016) Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production. Cell Metab 23:1154-66
Ackermann, Amanda M; Wang, Zhiping; Schug, Jonathan et al. (2016) Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes. Mol Metab 5:233-44
Henley, Kathryn D; Stanescu, Diana E; Kropp, Peter A et al. (2016) Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function. Cell Rep 15:2637-50
Tsai, Yu-Cheng; Cooke, Nancy E; Liebhaber, Stephen A (2016) Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster. Nucleic Acids Res 44:4651-64
Wang, Yue J; Schug, Jonathan; Won, Kyoung-Jae et al. (2016) Single-Cell Transcriptomics of the Human Endocrine Pancreas. Diabetes 65:3028-38
Tomar, Dhanendra; Dong, Zhiwei; Shanmughapriya, Santhanam et al. (2016) MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics. Cell Rep 15:1673-85
Wang, Yi; Frank, David B; Morley, Michael P et al. (2016) HDAC3-Dependent Epigenetic Pathway Controls Lung Alveolar Epithelial Cell Remodeling and Spreading via miR-17-92 and TGF-β Signaling Regulation. Dev Cell 36:303-15
Shearin, Abigail L; Monks, Bobby R; Seale, Patrick et al. (2016) Lack of AKT in adipocytes causes severe lipodystrophy. Mol Metab 5:472-9

Showing the most recent 10 out of 624 publications