The objective of the Functional Genomics Core is to provide state of the art experiment planning, sample preparation, quality assessment, microarray, DNA sequencing, and data analysis services to DRC members.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK019525-36
Application #
8310455
Study Section
Special Emphasis Panel (ZDK1-GRB-S (J1))
Project Start
Project End
Budget Start
2012-05-15
Budget End
2013-03-31
Support Year
36
Fiscal Year
2012
Total Cost
$174,645
Indirect Cost
$65,492
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Park, Hyeong-Kyu; Ahima, Rexford S (2015) Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism. Metabolism 64:24-34
Mulvey, Claire K; McNeill, Ann M; Girman, Cynthia J et al. (2014) Differential associations of oral glucose tolerance test-derived measures of insulin sensitivity and pancreatic *-cell function with coronary artery calcification and microalbuminuria in type 2 diabetes. Diabetes Care 37:124-33
Roe, Andrea; Hillman, Jennifer; Butts, Samantha et al. (2014) Decreased cholesterol efflux capacity and atherogenic lipid profile in young women with PCOS. J Clin Endocrinol Metab 99:E841-7
Soleimanpour, Scott A; Gupta, Aditi; Bakay, Marina et al. (2014) The diabetes susceptibility gene Clec16a regulates mitophagy. Cell 157:1577-90
Ferguson, Jane F; Mulvey, Claire K; Patel, Parth N et al. (2014) Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers. Mol Nutr Food Res 58:601-13
Tsai, Yu-Cheng; Cooke, Nancy E; Liebhaber, Stephen A (2014) Tissue specific CTCF occupancy and boundary function at the human growth hormone locus. Nucleic Acids Res 42:4906-21
Prenner, Stuart B; Mulvey, Claire K; Ferguson, Jane F et al. (2014) Very low density lipoprotein cholesterol associates with coronary artery calcification in type 2 diabetes beyond circulating levels of triglycerides. Atherosclerosis 236:244-50
Lee, Dolim; Le Lay, John; Kaestner, Klaus H (2014) The transcription factor CREB has no non-redundant functions in hepatic glucose metabolism in mice. Diabetologia 57:1242-8
Li, Ming; Li, Changhong; Allen, Aron et al. (2014) Glutamate dehydrogenase: structure, allosteric regulation, and role in insulin homeostasis. Neurochem Res 39:433-45
Naidoo, Nirinjini; Davis, James G; Zhu, Jingxu et al. (2014) Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell 13:131-41

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