- Pilot and Feasibility Program The purpose of the Michigan Diabetes Research Center (MDRC) Pilot and Feasibility (P/F) Grants Program is to stimulate new research in the areas of diabetes, its complications, and related endocrine and metabolic disorders. This research may be in areas of basic biomedical science or clinical research. This program provides a minimum of $250,000 per year for P/F grant awards; additional funding may be provided for highly-rated applications using funds provided by the University of Michigan. The MDRC P/F program will fund two types of awards: (1) standard one-year $50,000 P/F awards with a single PI, and (2) two-year, $100,000 Diabetes Interdisciplinary Studies Program (DISP) awards that seek to support and promote new collaborations between two or more University of Michigan (UM) faculty members from distinct disciplines, to focus their combined research strengths on cutting-edge areas in diabetes research. Each year, the MDRC solicits applications for P/F and DISP grants from full-time instructional or research faculty at UM. Those eligible include: 1) new investigators without past or current NIH research support who are beginning careers in diabetes research, 2) established investigators who have not previously worked in diabetes research but wish to focus their expertise on diabetes, and 3) established diabetes investigators who propose innovative research in diabetes that represents a clear departure from their ongoing research. Highest priority is given to new investigators. Applications are actively solicited from across the university and are peer-reviewed by two or more extramural reviewers with expertise in the area of the application. Grant applications with the highest merit, as judged by this review process and the intramural Grants Program Advisory Council, receive awards. The balance of standard P/F and DISP awards may vary from year to year, depending upon the relative strength of applications for each award type. The ultimate goal of the program is to enable awardees to generate sufficient preliminary data to support a successful application for major research funding from the NIH or another national granting agency. The P/F Grants Program attracts investigators from diverse schools, departments, and institutes into diabetes research and fosters new, innovative, interdisciplinary, and collaborative diabetes research at UM.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK020572-42
Application #
9657013
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2018-12-01
Budget End
2019-11-30
Support Year
42
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Meng, Zhuo-Xian; Tao, Weiwei; Sun, Jingxia et al. (2018) Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle. Diabetes 67:85-97
Burghardt, Kyle J; Seyoum, Berhane; Mallisho, Abdullah et al. (2018) Atypical antipsychotics, insulin resistance and weight; a meta-analysis of healthy volunteer studies. Prog Neuropsychopharmacol Biol Psychiatry 83:55-63
Wang, Ting; Pehrsson, Erica C; Purushotham, Deepak et al. (2018) The NIEHS TaRGET II Consortium and environmental epigenomics. Nat Biotechnol 36:225-227
Burghardt, Kyle J; Seyoum, Berhane; Dass, Sabrina E et al. (2018) Association of Protein Kinase B (AKT) DNA Hypermethylation with Maintenance Atypical Antipsychotic Treatment in Patients with Bipolar Disorder. Pharmacotherapy 38:428-435
Allison, Margaret B; Pan, Warren; MacKenzie, Alexander et al. (2018) Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action. Diabetes 67:1093-1104
Ray, Debashree; Boehnke, Michael (2018) Methods for meta-analysis of multiple traits using GWAS summary statistics. Genet Epidemiol 42:134-145
Pesch, Megan H; Miller, Alison L; Appugliese, Danielle P et al. (2018) Mothers of Obese Children Use More Direct Imperatives to Restrict Eating. J Nutr Educ Behav 50:403-407.e1
Pan, Warren; Adams, Jessica M; Allison, Margaret B et al. (2018) Essential Role for Hypothalamic Calcitonin Receptor?Expressing Neurons in the Control of Food Intake by Leptin. Endocrinology 159:1860-1872
Sherman, Shermel B; Sarsour, Nadeen; Salehi, Marziyeh et al. (2018) Prenatal androgen exposure causes hypertension and gut microbiota dysbiosis. Gut Microbes 9:400-421
Yu, Sangho; Cheng, Helia; François, Marie et al. (2018) Preoptic leptin signaling modulates energy balance independent of body temperature regulation. Elife 7:

Showing the most recent 10 out of 1823 publications