Abstract

The overall goal of the CURE: DDRCC is to promote multidisciplinary research in the molecular and cell biology, physiology and pathophysiology of the digestive system, foster collaboration and facilitate training, education and recruitment of new investigators. The Pilot and Feasibility Studies (PFS) Program, which has been enhanced by partnering with the UCLA Center for Translational Science Institute (CTSI) and by direct institutional resources (see below), is a key component to achieve the goals of the Center. The leverage of PFS funds has provided an important mechanism for enhancing our PFS program via substantial institutional support. We anticipate that a similar enhancement of the PFS program will operate in the next funding period.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK041301-28
Application #
9197997
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2016-12-01
Budget End
2017-11-30
Support Year
28
Fiscal Year
2017
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Park, S H; Naliboff, B D; Shih, W et al. (2018) Resilience is decreased in irritable bowel syndrome and associated with symptoms and cortisol response. Neurogastroenterol Motil 30:
Dong, Tien; Pisegna, Joseph (2018) Passing the ""Acid Test"": Do Proton Pump Inhibitors Affect the Composition of the Microbiome? Dig Dis Sci :
Basheer, Wassim A; Fu, Ying; Shimura, Daisuke et al. (2018) Stress response protein GJA1-20k promotes mitochondrial biogenesis, metabolic quiescence, and cardioprotection against ischemia/reperfusion injury. JCI Insight 3:
Jacobs, Jonathan P; Dong, Tien S; Agopian, Vatche et al. (2018) Microbiome and bile acid profiles in duodenal aspirates from patients with liver cirrhosis: The Microbiome, Microbial Markers and Liver Disease Study. Hepatol Res :
Sala-Rabanal, Monica; Ghezzi, Chiara; Hirayama, Bruce A et al. (2018) Intestinal absorption of glucose in mice as determined by positron emission tomography. J Physiol 596:2473-2489
Lin, De-Chen; Dinh, Huy Q; Xie, Jian-Jun et al. (2018) Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas. Gut 67:1769-1779
Tsang, Eric J; Wu, Benjamin; Zuk, Patricia (2018) MAPK signaling has stage-dependent osteogenic effects on human adipose-derived stem cells in vitro. Connect Tissue Res 59:129-146
Bhattarai, Yogesh; Williams, Brianna B; Battaglioli, Eric J et al. (2018) Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion. Cell Host Microbe 23:775-785.e5
Osadchiy, Vadim; Labus, Jennifer S; Gupta, Arpana et al. (2018) Correlation of tryptophan metabolites with connectivity of extended central reward network in healthy subjects. PLoS One 13:e0201772
May, Folasade P; Yu, Christine; Kaunitz, Jonathan (2018) High quality of cancer care in the Department of Veterans Affairs (VA). Am J Cancer Res 8:761-762

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