The Morphology Core will be co-directed by Atul Bhan and Dennis Brown. Services offered through the Morphology Core include routine tissue fixation and processing for light microscopy, perfusion-fixation of organs, conventional electron microscopy, low-temperature embedding, immunocytochemistry, laser scanning confocal microscopy, spinning disk confocal microscopy, total internal reflection fluorescence microscopy, calcium/pH ratio imaging, multiphoton confocal microscopy, helium ion microscopy, imaging flow cytometry, a central antibody bank, and extensive training opportunities. The Morphology Core offers cost-effective services that would otherwise represent substantial and prohibitive commitments in terms of purchase, management, and upkeep for any individual investigator. The Core was therefore established with a minimum outlay of funds and yet has at its disposal extremely well equipped laboratories, highly sophisticated microscope equipment, and state-of-the-art technology.
The specific aims of the Morphology Core are to (1) continue to provide a cost-effective and efficient solution for the morphology and imaging needs of the CSIBD user base via sophisticated instrumentation and outstanding intellectual and technical support; (2) generate an environment appropriate for the training of key personnel from participating laboratories; (3) strive to continually upgrade equipment and available techniques to allow the user base to stay at the cutting edge of cell and tissue imaging procedures; and (4) provide a central location for imaging activities in which different investigators can interact and share ideas for pushing IBD research forward.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK043351-28
Application #
9399648
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2018-01-01
Budget End
2018-12-31
Support Year
28
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02114
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