Abstract

A. Purpose ? To provide a service facilitv that will utilize investigator-derived DNA constructs or investigator derived (or obtained) genetically modified embryonic stem cells to create founder transgenic and gene knockout or knockin mice (i.e mice bearing point mutants, lox-modified or ires/2A-Cre knockin alleles) that can be used to address questions relevant to obesity, diabetes and nutrition, including questions related to brain control of feeding, metabolism and reward. ? To provide consultation and training on all aspects of making and using genetically modified mice.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK046200-21
Application #
8509881
Study Section
Special Emphasis Panel (ZDK1-GRB-2 (J3))
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
21
Fiscal Year
2013
Total Cost
$254,654
Indirect Cost

  Institution

Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118

  Publications

Marron, Elena M; Viejo-Sobera, Raquel; Cuatrecasas, Guillem et al. (2018) Prefronto-cerebellar neuromodulation affects appetite in obesity. Int J Obes (Lond) :
Dong, Kimberly R; Must, Aviva; Tang, Alice M et al. (2018) Food Insecurity, Morbidities, and Substance Use in Adults on Probation in Rhode Island. J Urban Health 95:564-575
Chiu, Yu-Han; Bertrand, Kimberly A; Zhang, Shumin et al. (2018) A prospective analysis of circulating saturated and monounsaturated fatty acids and risk of non-Hodgkin lymphoma. Int J Cancer 143:1914-1922
Yamamoto, Ayae; Harris, Holly R; Vitonis, Allison F et al. (2018) A prospective cohort study of meat and fish consumption and endometriosis risk. Am J Obstet Gynecol 219:178.e1-178.e10
Todd, William D; Fenselau, Henning; Wang, Joshua L et al. (2018) A hypothalamic circuit for the circadian control of aggression. Nat Neurosci 21:717-724
Perng, Wei; Rifas-Shiman, Sheryl L; Hivert, Marie-France et al. (2018) Branched Chain Amino Acids, Androgen Hormones, and Metabolic Risk Across Early Adolescence: A Prospective Study in Project Viva. Obesity (Silver Spring) 26:916-926
Kim, Hanseul; Keum, NaNa; Giovannucci, Edward L et al. (2018) Garlic intake and gastric cancer risk: Results from two large prospective US cohort studies. Int J Cancer 143:1047-1053
Heianza, Yoriko; Sun, Dianjianyi; Smith, Steven R et al. (2018) Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial. Diabetes Care 41:413-419
Chistol, Liem T; Bandini, Linda G; Must, Aviva et al. (2018) Sensory Sensitivity and Food Selectivity in Children with Autism Spectrum Disorder. J Autism Dev Disord 48:583-591
Thomas, Dylan D; Istfan, Nawfal W; Bistrian, Bruce R et al. (2018) Protein sparing therapies in acute illness and obesity: a review of George Blackburn's contributions to nutrition science. Metabolism 79:83-96

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