The overarching goals of the Administrative and Resource Access Core (ARAC) are to coordinate and integrate all activities of the Center, including Core reporting, P/F administration and enrichment activities. These organizational goals include promoting awareness of and interest in digestive disease related research through several linked mechanisms. First, the ARAC is committed to fostering and encouraging collaborative, trans-disciplinary research activities across the WU community through biomedical cores that provide enabling technology to its members with the goal of expanding research capacity. Secondly, the ARAC is committed to attracting investigators from other disciplines into digestive disease research and to promote these interests in trainees and junior faculty through an extensive Enrichment Program that includes research seminars, workshops and dedicated mentoring. Thirdly, the ARAC is committed to identifying and nurturing the careers of junior faculty interested in digestive disease through a rigorously peer reviewed Pilot/Feasibility Program that provides seed support for the most promising work. Fourthly, the ARAC is committed to promoting and enhancing synergies, among other NIDDK funded centers locally (DRC, NORC) as well as other DDRCCs regionally (through the Midwest Alliance)and nationally.
The Specific Aims for ARAC include:(1)Promote and enhance scientific dialog and collaboration centered on digestive disease among members spanning multiple departments and Centers, guided by a Steering Committee;(2) Organize and align core laboratories and services to provide state-of-the-art services and specialized expertise in line with members' needs;(3)0versee resource allocation through shared institutional Cores, guided by an Internal Executive Committee;(4)Review and align Research Base membership, guided by an Internal Executive Committee;(5)Assure stewardship of DDRCC resources in line with the needs of the Research Base and guided by an External Advisory Board;(6)Coordinate successful enrichment activities and promote career advancement of fellows and junior faculty interested in digestive disease research;(7)Assure dialog through web based communication, with other DDRCCs particularly those in the Midwest Alliance.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK052574-19
Application #
9393999
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2017-12-01
Budget End
2018-11-30
Support Year
19
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Engelstad, Holly J; Barron, Lauren; Moen, Joseph et al. (2018) Remnant Small Bowel Length in Pediatric Short Bowel Syndrome and the Correlation with Intestinal Dysbiosis and Linear Growth. J Am Coll Surg 227:439-449
Rusconi, B; Jiang, X; Sidhu, R et al. (2018) Gut Sphingolipid Composition as a Prelude to Necrotizing Enterocolitis. Sci Rep 8:10984
Knoop, Kathryn A; Newberry, Rodney D (2018) Goblet cells: multifaceted players in immunity at mucosal surfaces. Mucosal Immunol 11:1551-1557
Choi, Jaebok; Cooper, Matthew L; Staser, Karl et al. (2018) Baricitinib-induced blockade of interferon gamma receptor and interleukin-6 receptor for the prevention and treatment of graft-versus-host disease. Leukemia 32:2483-2494
Mills, Jason C; Samuelson, Linda C (2018) Past Questions and Current Understanding About Gastric Cancer. Gastroenterology 155:939-944
Vishy, Courtney E; Swietlicki, Elzbieta A; Gazit, Vered et al. (2018) Epimorphin regulates the intestinal stem cell niche via effects on the stromal microenvironment. Am J Physiol Gastrointest Liver Physiol 315:G185-G194
Brown, Jeffrey W; Badahdah, Arwa; Iticovici, Micah et al. (2018) A Role for Salivary Peptides in the Innate Defense Against Enterotoxigenic Escherichia coli. J Infect Dis 217:1435-1441
Wilen, Craig B; Lee, Sanghyun; Hsieh, Leon L et al. (2018) Tropism for tuft cells determines immune promotion of norovirus pathogenesis. Science 360:204-208
Ingle, Harshad; Peterson, Stefan T; Baldridge, Megan T (2018) Distinct Effects of Type I and III Interferons on Enteric Viruses. Viruses 10:
Wang, Xuanchuan; Xu, Min; Jia, Jianluo et al. (2018) CD47 blockade reduces ischemia/reperfusion injury in donation after cardiac death rat kidney transplantation. Am J Transplant 18:843-854

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