Abstract

A major impediment facing many laboratories interested in understanding basic genetic and physiological mechanisms, associated pathogenesis, or developing new treatments for nutrition and obesity-related disorders is access to relevant genetic animal models and resources needed to adequately test novel hypotheses. The AMC services as outlined in the specific aims and detailed below (section 4) describe how this core directly supports the basic needs of NORC investigators via complementary approaches using the most up to date technologies. The core provides innovative support to nutrition/obesity research by continuously testing and implementing newly developed instrumentation and methodologies (e.g. body composition analysis of zebrafish models, defined aquatic diets, new aquatic species, and new methods for creating genetically engineered mice).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK056336-12
Application #
8486418
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
12
Fiscal Year
2013
Total Cost
$144,863
Indirect Cost
$45,980

  Institution

Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Ejima, K; Pavela, G; Li, P et al. (2018) Generalized lambda distribution for flexibly testing differences beyond the mean in the distribution of a dependent variable such as body mass index. Int J Obes (Lond) 42:930-933
Watanabe, Louis P; Riddle, Nicole C (2018) Measuring Exercise Levels in Drosophila melanogaster Using the Rotating Exercise Quantification System (REQS). J Vis Exp :
Buford, Thomas W; Carter, Christy S; VanDerPol, William J et al. (2018) Composition and richness of the serum microbiome differ by age and link to systemic inflammation. Geroscience 40:257-268
Smith Jr, D L; Thomas, D M; Siu, C O et al. (2018) Regression to the mean, apparent data errors and biologically extraordinary results: letter regarding 'changes in telomere length 3-5 years after gastric bypass surgery'. Int J Obes (Lond) 42:949-950
George, Brandon J; Li, Peng; Lieberman, Harris R et al. (2018) Randomization to randomization probability: Estimating treatment effects under actual conditions of use. Psychol Methods 23:337-350
Ejima, Keisuke; Thomas, Diana M; Allison, David B (2018) A Mathematical Model for Predicting Obesity Transmission with Both Genetic and Nongenetic Heredity. Obesity (Silver Spring) 26:927-933
Dhurandhar, Emily J; Pavela, Gregory; Kaiser, Kathryn A et al. (2018) Body Mass Index and Subjective Social Status: The Coronary Artery Risk Development in Young Adults Study. Obesity (Silver Spring) 26:426-431
Schneider, C R; Biggio, J R; Chandler-Laney, P C (2018) Association of early pregnancy body mass index with post-partum weight change among African-American women. Clin Obes 8:170-175
Kim, Teayoun; Nason, Shelly; Holleman, Cassie et al. (2018) Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21. Diabetes 67:1773-1782
Borges, Juliano H; Carter, Stephen J; Singh, Harshvardhan et al. (2018) Inverse relationship between changes of maximal aerobic capacity and changes in walking economy after weight loss. Eur J Appl Physiol :

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