- Nutrigenetics Core In this competing renewal, the UNC NORC proposes to develop a new core, the Nutrigenetics (NGx) Core, that will assist our research base to identify genetic factors and interactions that affect an individual's needs and responses to nutrients and susceptibility to obesity, and to identify high-utility targets for prevention and treatment. During the next 5 years, this Core will be funded at a level of $55,000 per year, and it is expected that the core will mature and develop a demonstrated user base during this period. The NGx Core provides services including i) assistance with grant proposal submission (hypothesis development, study design, power calculations and generation of preliminary data); ii) study implementation (collection of data and samples); iii) laboratory services (sample processing, genetic and metabolic analyses, assay brokerage); iv) data entry and bioinformatics services; v) data analysis & interpretation and dissemination of results. The Core benefits a wide range of investigators such as nutrition epidemiologists, psychologists, geneticists and physicians who want to enhance their scientific capabilities by incorporating nutrigenetics components into human studies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK056350-16
Application #
9094773
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2016-04-01
Budget End
2017-03-31
Support Year
16
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Yuan, Ya-Qun; Li, Fan; Wu, Han et al. (2018) Evaluation of the Validity and Reliability of the Chinese Healthy Eating Index. Nutrients 10:
Ye, Zirong; Xu, Li; Zhou, Zi et al. (2018) Application of SCM with Bayesian B-Spline to Spatio-Temporal Analysis of Hypertension in China. Int J Environ Res Public Health 15:
Nieman, David C; Goodman, Courtney L; Capps, Christopher R et al. (2018) Influence of 2-Weeks Ingestion of High Chlorogenic Acid Coffee on Mood State, Performance, and Postexercise Inflammation and Oxidative Stress: A Randomized, Placebo-Controlled Trial. Int J Sport Nutr Exerc Metab 28:55-65
Keith, Benjamin P; Barrow, Jasmine B; Toyonaga, Takahiko et al. (2018) Colonic epithelial miR-31 associates with the development of Crohn's phenotypes. JCI Insight 3:
Barrington, William T; Wulfridge, Phillip; Wells, Ann E et al. (2018) Improving Metabolic Health Through Precision Dietetics in Mice. Genetics 208:399-417
Blue, R Eric; Koushik, Amrita; Engels, Nichlas M et al. (2018) Modulation of alternative splicing of trafficking genes by genome editing reveals functional consequences in muscle biology. Int J Biochem Cell Biol 105:134-143
Yu, Alice Yunzi L; López-Olmedo, Nancy; Popkin, Barry M (2018) Analysis of dietary trends in Chinese adolescents from 1991 to 2011. Asia Pac J Clin Nutr 27:1106-1119
Lacko, Allison M; Popkin, Barry M; Smith Taillie, Lindsey (2018) Grocery Stores Are Not Associated with More Healthful Food for Participants in the Supplemental Nutrition Assistance Program. J Acad Nutr Diet :
Chen, Chen; Modrek, Sepideh (2018) Gendered impact of solid fuel use on acute respiratory infections in children in China. BMC Public Health 18:1170
Buglak, Nicholas E; Jiang, Wulin; Bahnson, Edward S M (2018) Cinnamic aldehyde inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in Zucker Diabetic Fatty rats. Redox Biol 19:166-178

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