The Administrative Core plays a key role in coordinating the interactions among the broad and diverse elements of the Cystic Fibrosis Research Center (CFRC) of the University of Pittsburgh. Dr. Raymond A. Frizzell is the Core Center Director, and he is assisted by the Associate Director, Dr. Joseph Pilewski. Together, they oversee the Center's scientific and administrative operations. Dr. Frizzell has a long-standing commitment to CF research and an even longer record of continuous NIH support. He will: ? Work closely with the Center Committee to integrate the program and its scientific interactions within the University and with outside collaborators, its interactions with the NIDDK concerning plans and progress reports and information transfer to the lay community, ? Monitor the utilization, effective operation and use priorities of the Research Cores, ? Assure quality control concerning the selection and execution of pilot/feasibility studies, and ? Organize and operate an annual review of these activities by the Center's Internal and External Advisory Committees. Ms. Cindy Pokora (administrative assistant to Dr. Frizzell) will be responsible for coordinating the activities of the Center's interactive components (scheduling seminars, joint lab meetings, journal clubs, bimonthly meetings of the Center Committee, annual meetings of the Internal and External Advisory Committees) and maintain Center website content. She will prepare Progress Reports, facilitate interactions with outside agencies (NIH and CFF) and collaborators, and oversee the production and distribution of regular budget reports from the accounting staff to Core and Pilot PIs.

Public Health Relevance

The Administrative Core is the organizing focus for the CF Research Center and the P30 Core Center. It monitors core use, assures qualitty control of the cores and pilot/feasibility projects, organizes the annual Center review and communicates outcomes to the NIDDK, University and lay communities.

Agency
National Institute of Health (NIH)
Type
Center Core Grants (P30)
Project #
5P30DK072506-10
Application #
8685246
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Fazzari, Marco; Trostchansky, Andrés; Schopfer, Francisco J et al. (2014) Olives and olive oil are sources of electrophilic fatty acid nitroalkenes. PLoS One 9:e84884
Chen, Jingxin; Kleyman, Thomas R; Sheng, Shaohu (2014) Deletion of ?-subunit exon 11 of the epithelial Na+ channel reveals a regulatory module. Am J Physiol Renal Physiol 306:F561-7
Goetzman, Eric S; Alcorn, John F; Bharathi, Sivakama S et al. (2014) Long-chain acyl-CoA dehydrogenase deficiency as a cause of pulmonary surfactant dysfunction. J Biol Chem 289:10668-79
Gruber, Wolfgang; Orenstein, David M; Braumann, Klaus M et al. (2014) Interval exercise training in cystic fibrosis -- effects on exercise capacity in severely affected adults. J Cyst Fibros 13:86-91
Bomberger, Jennifer M; Ely, Kenneth H; Bangia, Naveen et al. (2014) Pseudomonas aeruginosa Cif protein enhances the ubiquitination and proteasomal degradation of the transporter associated with antigen processing (TAP) and reduces major histocompatibility complex (MHC) class I antigen presentation. J Biol Chem 289:152-62
Brodsky, Jeffrey L (2014) The threads that tie protein-folding diseases. Dis Model Mech 7:3-4
Yasuoka, Hidekata; Yamaguchi, Yukie; Feghali-Bostwick, Carol A (2014) The membrane-associated adaptor protein DOK5 is upregulated in systemic sclerosis and associated with IGFBP-5-induced fibrosis. PLoS One 9:e87754
Hendricks, Matthew R; Bomberger, Jennifer M (2014) Who's really in control: microbial regulation of protein trafficking in the epithelium. Am J Physiol Cell Physiol 306:C187-97
Xu, Zhe; Pissarra, Luísa S; Farinha, Carlos M et al. (2014) Revertant mutants modify, but do not rescue, the gating defect of the cystic fibrosis mutant G551D-CFTR. J Physiol 592:1931-47
Kang, Yanlong; Taldone, Tony; Patel, Hardik J et al. (2014) Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70. J Med Chem 57:1188-207

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