The overall objective of the Animal Models Facilities Core (AMFC) is to provide Center members with state-of-the-art pathology support, transgenic resources and a centrally managed AAALAC-approved animal resource and surgical facility. The Core is staffed with experienced personnel and is equipped with essential equipment to generate genetically engineered mice, rederive imported mice by embryo transfer rederivation, provide colony management, develop surgical models and prepare and interpret tissue samples by histological and immunohistochemistry analysis.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES002109-32
Application #
8375046
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2012-05-04
Budget End
2013-03-31
Support Year
32
Fiscal Year
2012
Total Cost
$234,773
Indirect Cost
$90,739
Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Chatterjee, Nimrat; Walker, Graham C (2017) Mechanisms of DNA damage, repair, and mutagenesis. Environ Mol Mutagen 58:235-263
Kwon, Ester J; Skalak, Matthew; Bertucci, Alessandro et al. (2017) Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections. Adv Mater 29:
HD iPSC Consortium (2017) Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice. Nat Neurosci 20:648-660
Samad, Tahoura; Billings, Nicole; Birjiniuk, Alona et al. (2017) Swimming bacteria promote dispersal of non-motile staphylococcal species. ISME J 11:1933-1937
Chai, Jiani N; Peng, Yangqing; Rengarajan, Sunaina et al. (2017) Helicobacter species are potent drivers of colonic T cell responses in homeostasis and inflammation. Sci Immunol 2:
Frydman, Galit H; Marini, Robert P; Bakthavatchalu, Vasudevan et al. (2017) Local and Systemic Changes Associated with Long-term, Percutaneous, Static Implantation of Titanium Alloys in Rhesus Macaques (Macaca mulatta). Comp Med 67:165-175
Kwon, Ester J; Dudani, Jaideep S; Bhatia, Sangeeta N (2017) Ultrasensitive tumour-penetrating nanosensors of protease activity. Nat Biomed Eng 1:
Baker, Tessa M; Nakashige, Toshiki G; Nolan, Elizabeth M et al. (2017) Magnetic circular dichroism studies of iron(ii) binding to human calprotectin. Chem Sci 8:1369-1377
Bodi Winn, C; Dzink-Fox, J; Feng, Y et al. (2017) Whole-Genome Sequences and Classification of Streptococcus agalactiae Strains Isolated from Laboratory-Reared Long-Evans Rats (Rattus norvegicus). Genome Announc 5:
Nakashige, Toshiki G; Nolan, Elizabeth M (2017) Human calprotectin affects the redox speciation of iron. Metallomics 9:1086-1095

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