Abstract

The goal of this renewal application for the NIEHS Center at EOHSI in Piscataway, NJ is to provide support and continuity to our mission of improving environmental and public health through research, education, outreach and communication. The EHS Center serves New Jersey, the most densely populated and perhaps the most heavily polluted state in the nation. The grant proposal consists of 4 Research Cores, 6 Facility Cores, a COEP and a Pilot Project Program. The Cores are as follows: I. Environment-Gene Interactions, II. Environmental Effects on Signal Transduction, III. Neural and Developmental Toxicology, IV. Exposure Analysis and Health Effects and Community Outreach and Education Program (COEP). Facility Cores are: Analytical Cytometry/Image Analysis, Biostatistics, Chemical Analysis, Molecular Genetics, Molecular Pathology and Proteomics.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES005022-22
Application #
7798138
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Reinlib, Leslie J
Project Start
1997-04-16
Project End
2014-01-31
Budget Start
2010-04-16
Budget End
2011-03-31
Support Year
22
Fiscal Year
2010
Total Cost
$1,687,674
Indirect Cost

  Institution

Name
University of Medicine & Dentistry of NJ
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
617022384
City
Piscataway
State
NJ
Country
United States
Zip Code
08854

  Publications

Venosa, Alessandro; Gow, James G; Hall, LeRoy et al. (2017) Regulation of Nitrogen Mustard-Induced Lung Macrophage Activation by Valproic Acid, a Histone Deacetylase Inhibitor. Toxicol Sci 157:222-234
Yang, Jennifer A; Stires, Hillary; Belden, William J et al. (2017) The Arcuate Estrogen-Regulated Transcriptome: Estrogen Response Element-Dependent and -Independent Signaling of ER? in Female Mice. Endocrinology 158:612-626
Hamm, Jon; Sullivan, Kristie; Clippinger, Amy J et al. (2017) Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing. Toxicol In Vitro 41:245-259
Fang, Mingzhu; Ohman Strickland, Pamela A; Kang, Hwan-Goo et al. (2017) Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis. Oncotarget 8:32752-32768
Russo, Daniel P; Kim, Marlene T; Wang, Wenyi et al. (2017) CIIPro: a new read-across portal to fill data gaps using public large-scale chemical and biological data. Bioinformatics 33:464-466
Bak, Min Ji; Das Gupta, Soumyasri; Wahler, Joseph et al. (2017) Inhibitory Effects of ?- and ?-Tocopherols on Estrogen-Stimulated Breast Cancer In Vitro and In Vivo. Cancer Prev Res (Phila) 10:188-197
George, Blessy; You, Dahea; Joy, Melanie S et al. (2017) Xenobiotic transporters and kidney injury. Adv Drug Deliv Rev 116:73-91
Joseph, Laurie B; Composto, Gabriella M; Perez, Roberto M et al. (2017) Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug. Toxicol Lett :
Garbuzenko, Olga B; Ivanova, Vera; Kholodovych, Vladislav et al. (2017) Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s). Nanomedicine 13:1983-1992
Sobolewski, Marissa; Weiss, Bernard; Martin, Melanie et al. (2017) Toxicoanthropology: Phthalate exposure in relation to market access in a remote forager-horticulturalist population. Int J Hyg Environ Health 220:799-809

Showing the most recent 10 out of 778 publications