Abstract

The goal of this renewal application for the NIEHS Center at EOHSI in Piscataway, NJ is to provide support and continuity to our mission of improving environmental and public health through research, education, outreach and communication. The EHS Center serves New Jersey, the most densely populated and perhaps the most heavily polluted state in the nation. The grant proposal consists of 4 Research Cores, 6 Facility Cores, a COEP and a Pilot Project Program. The Cores are as follows: I. Environment-Gene Interactions, II. Environmental Effects on Signal Transduction, III. Neural and Developmental Toxicology, IV. Exposure Analysis and Health Effects and Community Outreach and Education Program (COEP). Facility Cores are: Analytical Cytometry/Image Analysis, Biostatistics, Chemical Analysis, Molecular Genetics, Molecular Pathology and Proteomics.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
3P30ES005022-26S1
Application #
8737348
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Reinlib, Leslie J
Project Start
1997-04-16
Project End
2014-03-31
Budget Start
2013-09-20
Budget End
2014-03-31
Support Year
26
Fiscal Year
2013
Total Cost
$99,375
Indirect Cost
$36,875

  Institution

Name
Rbhs-Robert Wood Johnson Medical School
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
078795875
City
Piscataway
State
NJ
Country
United States
Zip Code
08854

  Publications

Szilagyi, John T; Fussell, Karma C; Wang, Yun et al. (2018) Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase. Toxicol Appl Pharmacol 359:102-107
Li, Wenji; Yang, Hilly; Buckley, Brian et al. (2018) A Novel Triple Stage Ion Trap MS method validated for curcumin pharmacokinetics application: A comparison summary of the latest validated curcumin LC/MS methods. J Pharm Biomed Anal 156:116-124
Cory-Slechta, D A; Allen, J L; Conrad, K et al. (2018) Developmental exposure to low level ambient ultrafine particle air pollution and cognitive dysfunction. Neurotoxicology 69:217-231
Joseph, Laurie B; Composto, Gabriella M; Perez, Roberto M et al. (2018) Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug. Toxicol Lett 293:77-81
Mamounis, Kyle J; Hernandez, Michelle R; Margolies, Nicholas et al. (2018) Interaction of 17?-estradiol and dietary fatty acids on energy and glucose homeostasis in female mice. Nutr Neurosci 21:715-728
Graber, Judith M; Chuang, Connie T; Ward, Carolyn L et al. (2018) Head and Neck Cancer in World Trade Center Responders: A Case Series. J Occup Environ Med 60:e439-e444
Stapleton, P A; McBride, C R; Yi, J et al. (2018) Estrous cycle-dependent modulation of in vivo microvascular dysfunction after nanomaterial inhalation. Reprod Toxicol 78:20-28
Dai, Zhuqing; Feng, Simin; Liu, Anna et al. (2018) Anti-inflammatory effects of newly synthesized ?-galacto-oligosaccharides on dextran sulfate sodium-induced colitis in C57BL/6J mice. Food Res Int 109:350-357
Graber, Judith M; Alexander, Cora; Laumbach, Robert J et al. (2018) Per and polyfluoroalkyl substances (PFAS) blood levels after contamination of a community water supply and comparison with 2013-2014 NHANES. J Expo Sci Environ Epidemiol :
Feng, Simin; Dai, Zhuqing; Liu, Anna B et al. (2018) Intake of stigmasterol and ?-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet. Biochim Biophys Acta Mol Cell Biol Lipids 1863:1274-1284

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