Abstract

The Integrative Health Sciences Facility Core (IHSFC) will enhance translation of research findings of studies of environmental factors in disease causation. The overall objectives will be accomplished through 1) expert consultation services in medicine, epidemiology, statistics, exposure assessment, 2) cohorts with environmental exposure data and biorepositories, 3) informatics tools and Forth and Back clinical research conferences, seminars and workshops that will mesh information from various disciplines for translation to the bedside and public health. Through providing these services and access to technologies, this IHSFC will build capacity for research that integrates basic science with clinical research and public health. The goal of the Core is to accelerate the transfer of basic biomedical knowledge from the laboratory to clinical applications in prevention, early detection, new treatments and, ultimately, to prolong and enhance life. The IHSFC will capitalize on the potential for synergy with other CEG components such as the Community Outreach and Engagement Core (COEC), Career Development Program (CDP), the Integrated Technologies Support Core (ITSC), Bioinformatics Core and the Pilot Projects Program (PPP).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES006096-23
Application #
8832602
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
2016-03-31
Budget Start
2015-04-01
Budget End
2016-03-31
Support Year
23
Fiscal Year
2015
Total Cost
$185,640
Indirect Cost
$68,239

  Institution

Name
University of Cincinnati
Department
Type
DUNS #
041064767
City
Cincinnati
State
OH
Country
United States
Zip Code
45221

  Publications

Bhattacharya, Sukanta S; Yadav, Jagjit S (2018) Microbial P450 Enzymes in Bioremediation and Drug Discovery: Emerging Potentials and Challenges. Curr Protein Pept Sci 19:75-86
VonHandorf, Andrew; Sánchez-Martín, Francisco Javier; Biesiada, Jacek et al. (2018) Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes. Epigenetics 13:363-375
Giannini, Courtney M; Herrick, Robert L; Buckholz, Jeanette M et al. (2018) Comprehension and perceptions of study participants upon receiving perfluoroalkyl substance exposure biomarker results. Int J Hyg Environ Health 221:1040-1046
Haque, Sulsal-Ul; Niu, Liang; Kuhnell, Damaris et al. (2018) Differential expression and prognostic value of long non-coding RNA in HPV-negative head and neck squamous cell carcinoma. Head Neck 40:1555-1564
Zhang, Hongmei; Yolton, Kimberly; Webster, Glenys M et al. (2018) Prenatal and childhood perfluoroalkyl substances exposures and children's reading skills at ages 5 and 8years. Environ Int 111:224-231
Sharma, Manju; Zhang, Xiang; Huang, Shouxiong (2018) Integrate Imaging Flow Cytometry and Transcriptomic Profiling to Evaluate Altered Endocytic CD1d Trafficking. J Vis Exp :
Vuong, Ann M; Braun, Joseph M; Webster, Glenys M et al. (2018) Polybrominated diphenyl ether (PBDE) exposures and thyroid hormones in children at age 3?years. Environ Int 117:339-347
Pugh, Amanda M; Giannini, Courtney M; Pinney, Susan M et al. (2018) Characteristics and diagnosis of pregnancy and lactation associated breast cancer: Analysis of a self-reported regional registry. Am J Surg 216:809-812
Brunst, Kelly J; Tignor, Nicole; Just, Allan et al. (2018) Cumulative lifetime maternal stress and epigenome-wide placental DNA methylation in the PRISM cohort. Epigenetics 13:665-681
Alexander, Jacqueline; Teague, April M; Chen, Jing et al. (2018) Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy. PLoS One 13:e0190698

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