The NIEHS Center for Environmental Health in Northern Manhattan (CEHNM) brings together scientists, physicians, epidemiologists, biostatisticians and citizens in a partnership focusing on a central theme that stresses understanding and preventing the environmental components of disease. The 32 Center, investigators work in three disease areas: cancer, respiratory diseases and neurotoxicology/ neurodegenerative diseases. Members seek to identify and study environmental exposures that contribute to the pathophysiology of human disease;communicate these results to other researchers, impacted communities, and the public;and develop strategies for translating these findings to improve public health. Research ranges from basic mechanistic studies to animal models to population studies. Themes are centered around air toxics/bioaerosols, oxidative stress, gene-environment interactions, life course exposures, epigenetics and, our newest theme, climate and health. While much research is focused on a disadvantaged community that receives disproportionally high exposure to hazardous substances in NYC, other projects study effects of environmental exposures around the world. Research is facilitated by four service cores including: (1) Exposure Assessment, (2) Trace Metals, (3) Integrative Health Sciences and (4) Administrative. Flexible Working Groups (Biomass Combustion, Epigenetics, Environmental Determinants of Neurological Disease, Environmental Exposures across the Life Course, Climate and Health) bring together investigators across the disease areas to initiate new areas of collaboration. A successful Pilot Project Program brings in new investigators and ideas. Our Community Outreach and Engagement Core is an active collaboration between Center investigators and West Harlem Environmental Action (WE ACT), our primary community partner. Activities include community forums, national conferences, mentoring of high school students and various educational activities. The Career Development Program enhances the mentoring of junior faculty currently taking place within the CEHNM. An Executive Committee helps the Director administer the program while two Advisory Committees provide additional guidance.

Public Health Relevance

Environmental exposures are known to play an important role in several human diseases. Research being carried out in the CEHNM is defining sources and types of exposures, mechanisms-of action and health effects. The better understanding of environmentally related disease will lead to its prevention.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES009089-16
Application #
8664377
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Thompson, Claudia L
Project Start
1998-07-01
Project End
2018-03-31
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
16
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10032
Factor-Litvak, Pam; Susser, Ezra; Kezios, Katrina et al. (2016) Leukocyte Telomere Length in Newborns: Implications for the Role of Telomeres in Human Disease. Pediatrics 137:
Sedaghat, Ahmad R; Matsui, Elizabeth C; Baxi, Sachin N et al. (2016) Mouse Sensitivity is an Independent Risk Factor for Rhinitis in Children with Asthma. J Allergy Clin Immunol Pract 4:82-8.e1
Yan, Beizhan; Passow, Uta; Chanton, Jeffrey P et al. (2016) Sustained deposition of contaminants from the Deepwater Horizon spill. Proc Natl Acad Sci U S A 113:E3332-40
Hernández, Diana (2016) Understanding 'energy insecurity' and why it matters to health. Soc Sci Med 167:1-10
García-Chequer, A J; Méndez-Tenorio, A; Olguín-Ruiz, G et al. (2016) Overview of recurrent chromosomal losses in retinoblastoma detected by low coverage next generation sequencing. Cancer Genet 209:57-69
Perera, Frederica; Nolte, Emily L Roen; Wang, Ya et al. (2016) Bisphenol A exposure and symptoms of anxiety and depression among inner city children at 10-12 years of age. Environ Res 151:195-202
Louis, Elan D (2016) More Time with Tremor: The Experience of Essential Tremor Versus Parkinson's Disease Patients. Mov Disord Clin Pract 3:36-42
Maresca, Michelle M; Hoepner, Lori A; Hassoun, Abeer et al. (2016) Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort. Environ Health Perspect 124:514-20
Kleiman, Norman J; Quinn, Adrienne M; Fields, Kara G et al. (2016) Arsenite accumulation in the mouse eye. J Toxicol Environ Health A 79:339-41
Kuo, Sheng-Han; Lin, Chi-Ying; Wang, Jie et al. (2016) Deep brain stimulation and climbing fiber synaptic pathology in essential tremor. Ann Neurol 80:461-5

Showing the most recent 10 out of 772 publications