A.2. Objectives: Numerous investigators have a need for the analysis of trace metals to conduct their research in environmental health sciences. The objective of the Trace Metals Core Lab is to enable these investigators to obtain the required measurements of metals in biological samples in a scientifically valid and cost-effective manner. During the past grant cycle, numerous NIH Grant awards to CEHNM investigators assure that the Trace Metals Facility Core will continue to be a critically important analytical laboratory. New NIH awards to Drs. Ahsan [3 R01s], Barr, Gamble [2 R01s], Graziano (Superfund/3 projects), and Guilarte [3 R01s], and Louis all require assistance from this Core Lab. In particular, the recruitment in 2010 of Dr. Tomas Guilarte as the EHS Department Chair - whose research career has focused on the neurotoxic effects of Pb and Mn - has added new NlEHS-funded research projects that require trace metal laboratory support. This Core Laboratory provides method development for these metal analyses, standardization, and quality control. Biochemical analyses that help in the assessment ofthe physiological status ofthe subjects that are exposed to these metals are also conducted. We should note here that this laboratory is partially funded by our Superfund Research Program (SRP), which was recently renewed. The SRP funds roughly two-thirds of this laboratory;the R01 grant work is not supported by the SRP grant and requires P30 Center support. The two sources of funding are directly proportionate with the use ofthe Core by the two programs.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
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Environmental Health Sciences Review Committee (EHS)
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Columbia University (N.Y.)
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Burris, Heather H; Baccarelli, Andrea A (2017) Air pollution and in utero programming of poor fetal growth. Epigenomics 9:213-216
Reynolds, Lindsay M; Magid, Hoda S; Chi, Gloria C et al. (2017) Secondhand Tobacco Smoke Exposure Associations With DNA Methylation of the Aryl Hydrocarbon Receptor Repressor. Nicotine Tob Res 19:442-451
Liu, Miaomiao; Huang, Yining; Ma, Zongwei et al. (2017) Spatial and temporal trends in the mortality burden of air pollution in China: 2004-2012. Environ Int 98:75-81
Colicino, Elena; Wilson, Ander; Frisardi, Maria Chiara et al. (2017) Telomere Length, Long-Term Black Carbon Exposure, and Cognitive Function in a Cohort of Older Men: The VA Normative Aging Study. Environ Health Perspect 125:76-81
Miller, Rachel L; Zhang, Hanjie; Jezioro, Jacqueline et al. (2017) Reduced mouse allergen is associated with epigenetic changes in regulatory genes, but not mouse sensitization, in asthmatic children. Environ Res 156:619-624
Kioumourtzoglou, Marianthi-Anna; Power, Melinda C; Hart, Jaime E et al. (2017) The Association Between Air Pollution and Onset of Depression Among Middle-Aged and Older Women. Am J Epidemiol 185:801-809
Lee, Joan; Kalia, Vrinda; Perera, Frederica et al. (2017) Prenatal airborne polycyclic aromatic hydrocarbon exposure, LINE1 methylation and child development in a Chinese cohort. Environ Int 99:315-320
Parada Jr, Humberto; Steck, Susan E; Cleveland, Rebecca J et al. (2017) Genetic polymorphisms of phase I metabolizing enzyme genes, their interaction with lifetime grilled and smoked meat intake, and breast cancer incidence. Ann Epidemiol 27:208-214.e1
Pei, Sen; Shaman, Jeffrey (2017) Counteracting structural errors in ensemble forecast of influenza outbreaks. Nat Commun 8:925
Chen, Kai; Zhou, Lian; Chen, Xiaodong et al. (2017) Acute effect of ozone exposure on daily mortality in seven cities of Jiangsu Province, China: No clear evidence for threshold. Environ Res 155:235-241

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