The Pilot Projects Program (PPP) is an important benefit of CEHS membership. Since the inception of the Center, the PPP has been viewed as a central activity of the Center. The mission of the PPP is to provide seed money to Center members to enhance their ability to obtain outside funding In a new innovative area of environmentally related research, preferably In a multi-disciplinary context. As described below, the program has been used primarily to foster the development of: (1) junior faculty who are developing a research program in an area of environmental health research of relevance to the Center;(2) to assist senior faculty members shift to new areas of environment research;(3) attract new investigators to apply their expertise to an environmentally related health problem;and (4) physician/scientists.
These aims have driven our annual Program, including the announcements of the availability of the pilot project awards, the application review process, as well as the selection of pilot project awardees. The ultimate goal of the pilot project program is to invest in and support the development of investigators that will generate external funding to address significant problems in environmental health. To this end, our award recipients have been very successful in obtaining funding for applications subsequently submitted to external agencies, usually utilizing data generated as part of the PPP, despite the modest amount of each single pilot project award (see below). The Center's investment of $1,294,297 (for years 2001 through 2008) has yielded more than 28 times that amount of direct funding (= $36,931,902) to PPP Awardees from external sources, as shown below. In addition, publications resulting from the PPP awards continue to increase (n = 56), also shown below. These successes of our PPP investigators are reviewed below under the section on """"""""Accomplishments.""""""""

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES010126-14
Application #
8651478
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
14
Fiscal Year
2014
Total Cost
$103,113
Indirect Cost
$33,441
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Oliver-Williams, Clare; Howard, Annie Green; Navas-Acien, Ana et al. (2018) Cadmium body burden, hypertension, and changes in blood pressure over time: results from a prospective cohort study in American Indians. J Am Soc Hypertens 12:426-437.e9
Mayne, Stephanie L; Auchincloss, Amy H; Tabb, Loni Philip et al. (2018) Associations of Bar and Restaurant Smoking Bans With Smoking Behavior in the CARDIA Study: A 25-Year Study. Am J Epidemiol 187:1250-1258
Gray, Kathleen M (2018) From Content Knowledge to Community Change: A Review of Representations of Environmental Health Literacy. Int J Environ Res Public Health 15:
Pace, Nelson D; Desrosiers, Tania A; Carmichael, Suzan L et al. (2018) Antioxidant Consumption is Associated with Decreased Odds of Congenital Limb Deficiencies. Paediatr Perinat Epidemiol 32:90-99
Zheng, Xiaojing; O'Connell, Catherine M; Zhong, Wujuan et al. (2018) Discovery of Blood Transcriptional Endotypes in Women with Pelvic Inflammatory Disease. J Immunol 200:2941-2956
Orlow, Irene; Shi, Yang; Kanetsky, Peter A et al. (2018) The interaction between vitamin D receptor polymorphisms and sun exposure around time of diagnosis influences melanoma survival. Pigment Cell Melanoma Res 31:287-296
Herceg, Zdenko; Ghantous, Akram; Wild, Christopher P et al. (2018) Roadmap for investigating epigenome deregulation and environmental origins of cancer. Int J Cancer 142:874-882
Tappata, Manaswita; Eluri, Swathi; Perjar, Irina et al. (2018) Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis. Allergy 73:2088-2092
Little, Michael S; Pellock, Samuel J; Walton, William G et al. (2018) Structural basis for the regulation of ?-glucuronidase expression by human gut Enterobacteriaceae. Proc Natl Acad Sci U S A 115:E152-E161
Hoffman, Kate; Stapleton, Heather M; Lorenzo, Amelia et al. (2018) Prenatal exposure to organophosphates and associations with birthweight and gestational length. Environ Int 116:248-254

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