The theme of the UNC Center for Environmental Health and Susceptibility (UNC-CEHS) is translating interdisciplinary research on environmental health threats to improve public health in North Carolina. The Center encourages and facilitates collaborations among basic researchers, public health scientists, and clinicians to generate high impact discoveries that improve public health. The strategic vision is implemented by the Administrative Core which manages budgets, oversees the Facility Cores, evaluates and funds innovative pilot projects, sponsors seminars and symposia, supports developing careers, communicates with Center membership, prepares reports and newsletters, and tracks publications and grant proposals. The Center has three Facility Cores that facilitate biospecimen acquisition, molecular analyses, and data analysis and experimental design. These cores ensure dissemination of proven and innovative new technologies to environmental disease research. The Integrated Health Sciences Facility Core provides expertise in biospecimen processing and helps encourage new collaborations using clinical and population-based studies. The Biostatistics and Bioinformatics Facility Core provides expertise in study design, data analysis, training and methodology development that especially supports the application of powerful omics technologies. The Molecular Analysis Facility Core provides expertise and instrumentation for mass spectrometry, assessment of DNA damage and its responses, translational histopathology and the full complement of genotyping and genomics technology. Each of the cores is designed to enhance productivity of UNC-CEHS investigators. Three Translational Research focus areas are supported by the Center: environmental cancer, cardiopulmonary disease, and developmental disease. North Carolina exposures often are associated with multiple outcomes, and thus research on similar environmental health threats unifies center investigators, provides connectivity, and ensures integration of UNC-CEHS. Scientific studies benefit from multi-directional communication, led by the UNC-CEHS Community Outreach and Engagement Core, which provides a means to disseminate research discoveries to public health professionals, community health workers, susceptible populations, families and lifelong learners. The science and outreach projects are supported by a competitive Pilot Projects program that prioritizes junior faculty. UNC-CEHS also actively mentors and cultivates leadership of junior and mid-level career investigators to train the next generation of environmental health researchers. Through the Stakeholder Advisory Board and External Advisory Board the UNC-CEHS receives input on community concerns and feedback on Center effectiveness. UNC-CEHS serves North Carolina, and ultimately the southeastern United States and the nation with innovative and strategic scientific activities and community engagement.

Public Health Relevance

The theme of the UNC Center for Environmental Health and Susceptibility (UNC-CEHS) is translating interdisciplinary research on environmental health threats to improve public health in North Carolina. By utilizing cutting edge instrumentation and technologies available to CEHS members to conduct interdisciplinary research and community engagement activities in our state, the UNC-CEHS will reduce environmental health threats and improve the health of North Carolinians. The scientific and public health discoveries will ultimately be disseminated to advance national priorities in preventing environmental disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES010126-16
Application #
9281813
Study Section
Special Emphasis Panel (EHS (P3))
Program Officer
Thompson, Claudia L
Project Start
2000-02-01
Project End
2021-03-31
Budget Start
2017-04-01
Budget End
2018-03-31
Support Year
16
Fiscal Year
2017
Total Cost
$1,506,662
Indirect Cost
$515,437
Name
University of North Carolina Chapel Hill
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Mayne, Stephanie L; Auchincloss, Amy H; Tabb, Loni Philip et al. (2018) Associations of Bar and Restaurant Smoking Bans With Smoking Behavior in the CARDIA Study: A 25-Year Study. Am J Epidemiol 187:1250-1258
Oliver-Williams, Clare; Howard, Annie Green; Navas-Acien, Ana et al. (2018) Cadmium body burden, hypertension, and changes in blood pressure over time: results from a prospective cohort study in American Indians. J Am Soc Hypertens 12:426-437.e9
Pace, Nelson D; Desrosiers, Tania A; Carmichael, Suzan L et al. (2018) Antioxidant Consumption is Associated with Decreased Odds of Congenital Limb Deficiencies. Paediatr Perinat Epidemiol 32:90-99
Gray, Kathleen M (2018) From Content Knowledge to Community Change: A Review of Representations of Environmental Health Literacy. Int J Environ Res Public Health 15:
Orlow, Irene; Shi, Yang; Kanetsky, Peter A et al. (2018) The interaction between vitamin D receptor polymorphisms and sun exposure around time of diagnosis influences melanoma survival. Pigment Cell Melanoma Res 31:287-296
Zheng, Xiaojing; O'Connell, Catherine M; Zhong, Wujuan et al. (2018) Discovery of Blood Transcriptional Endotypes in Women with Pelvic Inflammatory Disease. J Immunol 200:2941-2956
Tappata, Manaswita; Eluri, Swathi; Perjar, Irina et al. (2018) Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis. Allergy 73:2088-2092
Herceg, Zdenko; Ghantous, Akram; Wild, Christopher P et al. (2018) Roadmap for investigating epigenome deregulation and environmental origins of cancer. Int J Cancer 142:874-882
Hoffman, Kate; Stapleton, Heather M; Lorenzo, Amelia et al. (2018) Prenatal exposure to organophosphates and associations with birthweight and gestational length. Environ Int 116:248-254
Little, Michael S; Pellock, Samuel J; Walton, William G et al. (2018) Structural basis for the regulation of ?-glucuronidase expression by human gut Enterobacteriaceae. Proc Natl Acad Sci U S A 115:E152-E161

Showing the most recent 10 out of 1900 publications