The Pilot Project Program is a key component of the Center of Excellence in Environmental Toxicology (CEET), The Pilot Project Program is aimed at funding new directions in environmental health research. These grants represent one vehicle by which the Center can continue to enrich, attract and support innovative research that may not be ready for direct NIH-funding, In addition, Pilot Projects can be used to fund collaborative research that may become a component of a multi-investigator award, the development of technologies that may benefit other CEET investigators, and to take the CEET into new directions. The Pilot Project Program serves to attract junior investigators and established faculty new to environmental health sciences to the CEET. The Program encourages applications that address community-based needs and can be proposed by COEC members. The Pilot Project Program also encourages applications that will seed patient and human population-based research that may require the resources of the Integrative Health Sciences Facility Core (IHSFC). This Program represents an important vehicle by which the Center can rejuvenate its membership and draw natural alliances with new faculty. The goals of the Pilot Project Program are to: ? Support career development of junior faculty in environmental health science ? Attract established investigators into environmental health science ? Develop technologies that may benefit other CEET investigators ? Fund collaborative research that may lead to multi-investigator grant applications ? Stimulate translational research themes in environmental health science ? Fund community based research projects identified by COEC members ? Fund patient and population based exposure research that will utilize the IHSFC The CEET is in its third year of funding and has awarded 14 Pilot Projects. Four of these awards were funded January 01, 2009. Of the ten Pilot Projects that have had sufficient time to provide a return on the investment, $4,085,050 in direct costs have been generated for an investment of $225,000 which is greater than 18:1. This value is deflated to 13.1: 1 if the newly funded Pilot Projects are counted. Pilot Project funding has led to 12 articles published in the scientific literature.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES013508-08
Application #
8449278
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
8
Fiscal Year
2013
Total Cost
$214,150
Indirect Cost
$78,076
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Nativio, Raffaella; Donahue, Greg; Berson, Amit et al. (2018) Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease. Nat Neurosci 21:497-505
Leas, Brian F; D'Anci, Kristen E; Apter, Andrea J et al. (2018) Effectiveness of indoor allergen reduction in asthma management: A systematic review. J Allergy Clin Immunol 141:1854-1869
McCauley, Katherine B; Alysandratos, Konstantinos-Dionysios; Jacob, Anjali et al. (2018) Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium. Stem Cell Reports 10:1579-1595
Li, Xinjian; Egervari, Gabor; Wang, Yugang et al. (2018) Regulation of chromatin and gene expression by metabolic enzymes and metabolites. Nat Rev Mol Cell Biol 19:563-578
Crawford, Nicholas; Prendergast, D'Arcy; Oehlert, John W et al. (2018) Divergent Patterns of Mitochondrial and Nuclear Ancestry Are Associated with the Risk for Preterm Birth. J Pediatr 194:40-46.e4
Morris, Scott; Vachani, Anil; Pass, Harvey I et al. (2018) Whole blood FPR1 mRNA expression predicts both non-small cell and small cell lung cancer. Int J Cancer 142:2355-2362
Malik, Dania M; Rhoades, Seth; Weljie, Aalim (2018) Extraction and Analysis of Pan-metabolome Polar Metabolites by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS). Bio Protoc 8:
Yousefi, Shida; Sharma, Satish K; Stojkov, Darko et al. (2018) Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. J Leukoc Biol 104:205-214
Mishra, Om P; Popov, Anatoliy V; Pietrofesa, Ralph A et al. (2018) Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits myeloperoxidase activity in inflammatory cells. Biochim Biophys Acta Gen Subj 1862:1364-1375
Hwang, Michael T; Wang, Zejun; Ping, Jinglei et al. (2018) DNA Nanotweezers and Graphene Transistor Enable Label-Free Genotyping. Adv Mater :e1802440

Showing the most recent 10 out of 835 publications