Abstract

The Systems Biology Core, directed by Eberhard Voit, is composed of an educational component and a service component. The goal of the core is to educate HERCULES investigators on how systems biology approaches can help generate data that can be used in higher-level exposome models. The service component will provide bioinformatic, biostatistical, and systems biology support for all HERCULES investigators. The Integrated Health Sciences Facility Core, directed by Dean Jones, will provide three central functions within the Center, support of clinical research services, personalized exposure surveillance using a top-down high-resolution metabolomics method and targeted exposure analysis using mass spectrometry, immunoassay and chemical sensor methods. The core will facilitate translational and clinical studies by providing access and expertise with several well-characterized human/clinical populations. The IHSFC will act at the interface of the exposome and clinical and public health practice.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES019776-02
Application #
8664390
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
2
Fiscal Year
2014
Total Cost
Indirect Cost

  Institution

Name
Emory University
Department
Type
DUNS #
City
Atlanta
State
GA
Country
United States
Zip Code
30322

  Publications

Runa, Sabiha; Hussey, Michael; Payne, Christine K (2018) Nanoparticle-Cell Interactions: Relevance for Public Health. J Phys Chem B 122:1009-1016
Kolluru, Chandana; Gomaa, Yasmine; Prausnitz, Mark R (2018) Development of a thermostable microneedle patch for polio vaccination. Drug Deliv Transl Res :
Davis, Jacob D; Voit, Eberhard O (2018) Metrics for Regulated Biochemical Pathway Systems. Bioinformatics :
Steves, Alyse N; Turry, Adam; Gill, Brittany et al. (2018) Per- and polyfluoroalkyl substances impact human spermatogenesis in a stem-cell-derived model. Syst Biol Reprod Med 64:225-239
Hu, Xin; Chandler, Joshua D; Fernandes, Jolyn et al. (2018) Selenium supplementation prevents metabolic and transcriptomic responses to cadmium in mouse lung. Biochim Biophys Acta Gen Subj :
Jacobson, Melanie H; Howards, Penelope P; Darrow, Lyndsey A et al. (2018) Thyroid hormones and menstrual cycle function in a longitudinal cohort of premenopausal women. Paediatr Perinat Epidemiol 32:225-234
Bettermann, Erika L; Hartman, Terryl J; Easley, Kirk A et al. (2018) Higher Mediterranean Diet Quality Scores and Lower Body Mass Index Are Associated with a Less-Oxidized Plasma Glutathione and Cysteine Redox Status in Adults. J Nutr 148:245-253
Thompson, Jeffrey A; Christensen, Brock C; Marsit, Carmen J (2018) Methylation-to-Expression Feature Models of Breast Cancer Accurately Predict Overall Survival, Distant-Recurrence Free Survival, and Pathologic Complete Response in Multiple Cohorts. Sci Rep 8:5190
Everson, Todd M; Marsit, Carmen J (2018) Integrating -Omics Approaches into Human Population-Based Studies of Prenatal and Early-Life Exposures. Curr Environ Health Rep 5:328-337
Ladva, Chandresh Nanji; Golan, Rachel; Liang, Donghai et al. (2018) Particulate metal exposures induce plasma metabolome changes in a commuter panel study. PLoS One 13:e0203468

Showing the most recent 10 out of 145 publications