The overall goal of the CTEHR Administrative Core is to provide a centralized organizational infrastructure that will effectively coordinate Center activities, provide fiscal oversight, and optimize use of Center resources. The Administrative Core will also maintain databases and documentation for Center membership, Facility Core usage and Center related reporting and compliance activities. As one of the primary roles of the Administrative Core is to ensure effective communication both within CTEHR and to external stakeholders, this Core will also maintain the Center website and membership listserves. The Administrative Core also plays a key role in organizing, coordinating and reporting meetings of the Center Executive and Internal Advisory Committees and the External Advisory Board, and will prepare and distribute reports to the membership and NIEHS. In addition, the Administrative Core will organize the CTEHR Seminar Series and the annual Center retreat, and will support Theme Leaders in their development of Integration Meetings and Opportunity Workshops. The Administrative Core will also provide support to the COEC for arranging Stakeholder Advisory Board meetings. To facilitate the Pilot Project Program activities and support utilization of Facility Cores, the Administrative Core will assure timely distribution of awards and provide Matching Funds support for member utilization of Cores. Thus, the Administrative Core plays a central role in the activities of the Center, and will further the mission of the CTEHR by fostering collaborative and synergistic research around Center themes, facilitating member access to cutting edge technologies, enhancing development of new and transitioning environmental health scientists and translating EHS research findings from bench, to bedside, and to the community and back.
Program Narrative-Administrative Core The Administrative Core is central to the public health mission of the CTEHR. This Core will provide the organizational infrastructure to coordinate Center activities and optimize use of Center resources. The Administrative Core will further the mission of the CTEHR by fostering collaborative and synergistic EHS research, facilitating member access to cutting edge technologies, enhancing development of new and transitioning environmental health scientists and translating EHS research findings from bench, to bedside, and to the community and back.
|Pogribny, Igor P; Dreval, Kostiantyn; Kindrat, Iryna et al. (2017) Epigenetically mediated inhibition of S-adenosylhomocysteine hydrolase and the associated dysregulation of 1-carbon metabolism in nonalcoholic steatohepatitis and hepatocellular carcinoma. FASEB J :|
|Dreval, Kostiantyn; de Conti, Aline; Furuya, Shinji et al. (2017) miR-1247 blocks SOX9-mediated regeneration in alcohol- and fibrosis-associated acute kidney injury in mice. Toxicology 384:40-49|
|Luo, Yu-Syuan; Cichocki, Joseph A; McDonald, Thomas J et al. (2017) Simultaneous detection of the tetrachloroethylene metabolites S-(1,2,2-trichlorovinyl) glutathione, S-(1,2,2-trichlorovinyl)-L-cysteine, and N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine in multiple mouse tissues via ultra-high performance liquid chromatog J Toxicol Environ Health A 80:513-524|
|Jin, Un-Ho; Cheng, Yating; Park, Hyejin et al. (2017) Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 Human Colon Cancer Cells. Sci Rep 7:10163|
|Grimm, Fabian A; Russell, William K; Luo, Yu-Syuan et al. (2017) Grouping of Petroleum Substances as Example UVCBs by Ion Mobility-Mass Spectrometry to Enable Chemical Composition-Based Read-Across. Environ Sci Technol 51:7197-7207|
|Banu, Sakhila K; Stanley, Jone A; Sivakumar, Kirthiram K et al. (2017) Chromium VI - Induced developmental toxicity of placenta is mediated through spatiotemporal dysregulation of cell survival and apoptotic proteins. Reprod Toxicol 68:171-190|
|Fuentes, Natividad R; Salinas, Michael L; Kim, Eunjoo et al. (2017) Emerging role of chemoprotective agents in the dynamic shaping of plasma membrane organization. Biochim Biophys Acta 1859:1668-1678|
|Cheng, Yating; Jin, Un-Ho; Davidson, Laurie A et al. (2017) Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling. Toxicol Sci 155:458-473|
|Lacey, Alexandra; Rodrigues-Hoffman, Aline; Safe, Stephen (2017) PAX3-FOXO1A Expression in Rhabdomyosarcoma Is Driven by the Targetable Nuclear Receptor NR4A1. Cancer Res 77:732-741|
|Kumar, Ritesh; Herold, Jennifer L; Schady, Deborah et al. (2017) Streptococcus gallolyticus subsp. gallolyticus promotes colorectal tumor development. PLoS Pathog 13:e1006440|
Showing the most recent 10 out of 135 publications