19 co-investigators propose renewal of a Vision Research Center core grant to support four service modules that will mediate increased research productivity. These modules will provide support services in instrumentation (machine and electronic shops), scientific illustration, computing and molecular biology. The vision research of the investigators falls into three divisions: Neural Systems, Cell and Molecular and Clinical. Investigators from each of the groups will benefit from the services of the instrumentation and illustration facilities. The computing facility will largely serve to permit testing of complex neural network models thought to account for various visual functions. It will also be used by some of the molecular group in protein structure and dynamics simulation. Molecular and Clinical investigators will use the molecular biology facility toward understanding protein function, cellular localization of specific e.g. neurotransmission and second messenger mechanisms and in generation, testing and gene therapy rescue of transgenic mice expressing various mutant genes found in human retinitis pigmentosa, cataract and other diseases of the eye.
| Bunya, Vatinee Y; Fernandez, Karen B; Ying, Gui-Shuang et al. (2018) Survey of Ophthalmologists Regarding Practice Patterns for Dry Eye and Sjogren Syndrome. Eye Contact Lens 44 Suppl 2:S196-S201 |
| Govorkova, Maria S; Milman, Tatyana; Ying, Gui-Shuang et al. (2018) Inflammatory Mediators in Xanthelasma Palpebrarum: Histopathologic and Immunohistochemical Study. Ophthalmic Plast Reconstr Surg 34:225-230 |
| Collins, David W; Gudiseva, Harini V; Chavali, Venkata R M et al. (2018) The MT-CO1 V83I Polymorphism is a Risk Factor for Primary Open-Angle Glaucoma in African American Men. Invest Ophthalmol Vis Sci 59:1751-1759 |
| Radonjic, Ana; Ding, Xiaomao; Krieger, Avery et al. (2018) Illumination discrimination in the absence of a fixed surface-reflectance layout. J Vis 18:11 |
| Song, Ji Yun; Aravand, Puya; Nikonov, Sergei et al. (2018) Amelioration of Neurosensory Structure and Function in Animal and Cellular Models of a Congenital Blindness. Mol Ther 26:1581-1593 |
| Dedania, Vaidehi S; Zacks, David N; Pan, Wei et al. (2018) TESTOSTERONE SUPPLEMENTATION AND RETINAL VASCULAR DISEASE. Retina 38:2247-2252 |
| Ying, Gui-Shuang; Maguire, Maureen G; Glynn, Robert et al. (2018) Tutorial on Biostatistics: Statistical Analysis for Correlated Binary Eye Data. Ophthalmic Epidemiol 25:1-12 |
| Tuten, William S; Cooper, Robert F; Tiruveedhula, Pavan et al. (2018) Spatial summation in the human fovea: Do normal optical aberrations and fixational eye movements have an effect? J Vis 18:6 |
| Sudharsan, Raghavi; Elliott, Michael H; Dolgova, Natalia et al. (2018) Photoreceptor Outer Segment Isolation from a Single Canine Retina for RPE Phagocytosis Assay. Adv Exp Med Biol 1074:593-601 |
| Cooper, Robert F; Tuten, William S; Dubra, Alfredo et al. (2018) Erratum: Non-invasive assessment of human cone photoreceptor function: erratum. Biomed Opt Express 9:1842 |
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