Abstract

Purpose: Gene Delivery Module Research aimed at understanding the development, physiology, and pathology ofthe visual system has been aided enormously by the advent of technologies for exogenously expressing foreign genes and inhibiting expression of endogenous genes. Over the past 5 years, the Gene Delivery Module (GDM) has played an important role in helping Berkeley Vision Science researchers employ these technologies, and has fostered collaborations among visual system labs. The Module two facilities in Barker and Minor Hall that have designed, prepared, and purified gene constructs specifically for somatic cell gene transfer to ocular tissues. It has also helped investigators create germline animal models of basic ocular processes and ocular disease.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY003176-32
Application #
8694036
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
32
Fiscal Year
2014
Total Cost
Indirect Cost

  Institution

Name
University of California Berkeley
Department
Type
DUNS #
City
Berkeley
State
CA
Country
United States
Zip Code
94704

  Publications

Tiriac, Alexandre; Smith, Benjamin E; Feller, Marla B (2018) Light Prior to Eye Opening Promotes Retinal Waves and Eye-Specific Segregation. Neuron 100:1059-1065.e4
Smith, Benjamin; Li, Jianfang; Metruccio, Matteo et al. (2018) Quantification of Bacterial Twitching Motility in Dense Colonies Using Transmitted Light Microscopy and Computational Image Analysis. Bio Protoc 8:
Gayet-Primo, Jacqueline; Yaeger, Daniel B; Khanjian, Roupen A et al. (2018) Heteromeric KV2/KV8.2 Channels Mediate Delayed Rectifier Potassium Currents in Primate Photoreceptors. J Neurosci 38:3414-3427
Piazza, Elise A; Denison, Rachel N; Silver, Michael A (2018) Recent cross-modal statistical learning influences visual perceptual selection. J Vis 18:1
Schmidt, Brian P; Sabesan, Ramkumar; Tuten, William S et al. (2018) Sensations from a single M-cone depend on the activity of surrounding S-cones. Sci Rep 8:8561
Mardinly, Alan R; Oldenburg, Ian Antón; Pégard, Nicolas C et al. (2018) Precise multimodal optical control of neural ensemble activity. Nat Neurosci 21:881-893
Wu, Yvonne T; Truong, Tan N; Tam, Connie et al. (2018) Impact of topical corticosteroid pretreatment on susceptibility of the injured murine cornea to Pseudomonas aeruginosa colonization and infection. Exp Eye Res 179:1-7
Agaoglu, Mehmet N; Sheehy, Christy K; Tiruveedhula, Pavan et al. (2018) Suboptimal eye movements for seeing fine details. J Vis 18:8
Morrie, Ryan D; Feller, Marla B (2018) A Dense Starburst Plexus Is Critical for Generating Direction Selectivity. Curr Biol 28:1204-1212.e5
Gao, Yuan; Su, John; Zhang, Yibing et al. (2018) Dietary DHA amplifies LXA4 circuits in tissues and lymph node PMN and is protective in immune-driven dry eye disease. Mucosal Immunol 11:1674-1683

Showing the most recent 10 out of 183 publications