Abstract

Fifty-two investigators from the Oregon Health &Science University are requesting renewal of National Eye Institute core funding to support four modules: Molecular genetics and statistics, Gene Expression, Proteomics, and Microscopy. Since its last core grant competing renewal 5 years ago, the department of ophthalmology has tripled its wet lab research space. The core users include 27 faculty members who are principal investigators on NEI supported grants, including 31 grants which are either R0Is or K08s, as well as 2 R21s and 1 R42. The investigators also receive additional NIH and foundation support. The Casey Eye Institute/Department of Ophthalmology has made a major commitment to research as should be apparent from this depth and from this growth. The core grant support from the NEI has been an essential component of this success. The department is committed to expanding its research program with core facilities serving as a major contributor to this projected growth.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY010572-18
Application #
8264350
Study Section
Special Emphasis Panel (ZEY1-VSN (03))
Program Officer
Liberman, Ellen S
Project Start
1997-05-01
Project End
2015-04-30
Budget Start
2012-05-01
Budget End
2013-04-30
Support Year
18
Fiscal Year
2012
Total Cost
$734,309
Indirect Cost
$257,485

  Institution

Name
Oregon Health and Science University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239

  Publications

Redd, Travis K; Campbell, J Peter; Chiang, Michael F (2018) Is This the Right Reference Standard Diagnosis for Retinopathy of Prematurity?-Reply. JAMA Ophthalmol 136:1429-1430
Kerov, Vasily; Laird, Joseph G; Joiner, Mei-Ling et al. (2018) ?2?-4 Is Required for the Molecular and Structural Organization of Rod and Cone Photoreceptor Synapses. J Neurosci 38:6145-6160
Manh, Vivian M; Holmes, Jonathan M; Lazar, Elizabeth L et al. (2018) A Randomized Trial of a Binocular iPad Game Versus Part-Time Patching in Children Aged 13 to 16 Years With Amblyopia. Am J Ophthalmol 186:104-115
Smith, Justine R; David, Larry L; Appukuttan, Binoy et al. (2018) Angiogenic and Immunologic Proteins Identified by Deep Proteomic Profiling of Human Retinal and Choroidal Vascular Endothelial Cells: Potential Targets for New Biologic Drugs. Am J Ophthalmol 193:197-229
McGill, Trevor J; Wilson, David J; Stoddard, Jonathan et al. (2018) Cell Transplantation for Retinal Degeneration: Transition from Rodent to Nonhuman Primate Models. Adv Exp Med Biol 1074:641-647
Biten, Hilal; Redd, Travis K; Moleta, Chace et al. (2018) Diagnostic Accuracy of Ophthalmoscopy vs Telemedicine in Examinations for Retinopathy of Prematurity. JAMA Ophthalmol 136:498-504
Boese, Erin A; Karr, Daniel J; Chiang, Michael F et al. (2018) Visual acuity recovery following traumatic hyphema in a pediatric population. J AAPOS 22:115-118
Zhu, Li; Zong, Yuan; Yu, Jian et al. (2018) Reduced Retinal Vessel Density in Primary Angle Closure Glaucoma: A Quantitative Study Using Optical Coherence Tomography Angiography. J Glaucoma 27:322-327
Raghunathan, Vijay Krishna; Benoit, Julia; Kasetti, Ramesh et al. (2018) Glaucomatous cell derived matrices differentially modulate non-glaucomatous trabecular meshwork cellular behavior. Acta Biomater 71:444-459
Jiang, Xiaoyun; Johnson, Elaine; Cepurna, William et al. (2018) The effect of age on the response of retinal capillary filling to changes in intraocular pressure measured by optical coherence tomography angiography. Microvasc Res 115:12-19

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