Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
1P30EY011373-01A1
Application #
6239873
Study Section
Project Start
1997-04-01
Project End
1998-03-31
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Basak, Sandip; Gicheru, Yvonne; Samanta, Amrita et al. (2018) Cryo-EM structure of 5-HT3A receptor in its resting conformation. Nat Commun 9:514
Mamidi, Ranganath; Li, Jiayang; Doh, Chang Yoon et al. (2018) Impact of the Myosin Modulator Mavacamten on Force Generation and Cross-Bridge Behavior in a Murine Model of Hypercontractility. J Am Heart Assoc 7:e009627
Basak, Sandip; Gicheru, Yvonne; Rao, Shanlin et al. (2018) Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3A receptor. Nature 563:270-274
Gao, Songqi; Parmar, Tanu; Palczewska, Grazyna et al. (2018) Protective Effect of a Locked Retinal Chromophore Analog against Light-Induced Retinal Degeneration. Mol Pharmacol 94:1132-1144
Malemud, Charles J (2018) The role of the JAK/STAT signal pathway in rheumatoid arthritis. Ther Adv Musculoskelet Dis 10:117-127
Clark, Heather L; Minns, Martin S; Sun, Yan et al. (2018) Atovaquone Impairs Growth of Aspergillus and Fusarium Keratitis Isolates by Modulating Mitochondrial Function and Zinc Homeostasis. Invest Ophthalmol Vis Sci 59:1589-1598
Parmar, Tanu; Parmar, Vipul M; Perusek, Lindsay et al. (2018) Lipocalin 2 Plays an Important Role in Regulating Inflammation in Retinal Degeneration. J Immunol 200:3128-3141
Widjaja-Adhi, Made Airanthi K; Ramkumar, Srinivasagan; von Lintig, Johannes (2018) Protective role of carotenoids in the visual cycle. FASEB J :fj201800467R
Chen, Yuanyuan; Chen, Yu; Jastrzebska, Beata et al. (2018) A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration. Nat Commun 9:1976
Mast, Natalia; Bederman, Ilya R; Pikuleva, Irina A (2018) Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol. Drug Metab Dispos 46:1528-1537

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