Abstract

The Center for Neural Science at New York University is a premier site for research on functional aspects of vision. Eighteen investigators from the Center request support for their vision research through continuation of a Core Grant. They are bound together by their research interests in the neural and behavioral bases of vision and visually guided behavior. The proposed Core will comprise four modules, each of which will benefit research in the research areas represented by program faculty: a Visual Displays Module, a Design and Fabrication Module, a Neuroanatomy Module, and a Functional Imaging Module.

Public Health Relevance

The work of the members of the Vision Core at the Center for Neural Science at New York University seeks to understand the functional basis for vision and visually guided behavior, and the way in which these are disrupted by disease. To enhance this work, we request continuation of a Core Grant, comprising four modules, each of which will benefit research in the areas represented by members of the core and enhance their contribution to understanding vision in health and disease.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY013079-18
Application #
9341319
Study Section
Special Emphasis Panel (ZEY1)
Program Officer
Liberman, Ellen S
Project Start
2000-04-01
Project End
2020-06-30
Budget Start
2017-07-01
Budget End
2018-06-30
Support Year
18
Fiscal Year
2017
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Neurosciences
Type
Schools of Arts and Sciences
DUNS #
041968306
City
New York
State
NY
Country
United States
Zip Code
10012

  Publications

Aoki, Chiye; Chen, Yi-Wen; Chowdhury, Tara Gunkali et al. (2018) ?4??-GABAA receptors in dorsal hippocampal CA1 of adolescent female rats traffic to the plasma membrane of dendritic spines following voluntary exercise and contribute to protection of animals from activity-based anorexia through localization at excitator J Neurosci Res 96:1450-1466
Chen, Yi-Wen; Actor-Engel, Hannah; Aoki, Chiye (2018) ?4-GABAA receptors of hippocampal pyramidal neurons are associated with resilience against activity-based anorexia for adolescent female mice but not for males. Mol Cell Neurosci 90:33-48
Aoki, Chiye; Chowdhury, Tara G; Wable, Gauri S et al. (2017) Synaptic changes in the hippocampus of adolescent female rodents associated with resilience to anxiety and suppression of food restriction-evoked hyperactivity in an animal model for anorexia nervosa. Brain Res 1654:102-115
Nedelescu, Hermina; Chowdhury, Tara G; Wable, Gauri S et al. (2017) Cerebellar sub-divisions differ in exercise-induced plasticity of noradrenergic axons and in their association with resilience to activity-based anorexia. Brain Struct Funct 222:317-339
Chen, Yi-Wen; Actor-Engel, Hannah; Sherpa, Ang Doma et al. (2017) NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise. Brain Struct Funct 222:2271-2294
Santiago, Adrienne; Aoki, Chiye; Sullivan, Regina M (2017) From attachment to independence: Stress hormone control of ecologically relevant emergence of infants' responses to threat. Curr Opin Behav Sci 14:78-85
Shen, Hui; Sabaliauskas, Nicole; Yang, Lie et al. (2017) Role of ?4-containing GABAA receptors in limiting synaptic plasticity and spatial learning of female mice during the pubertal period. Brain Res 1654:116-122
Kelly, Jenna G; Hawken, Michael J (2017) Quantification of neuronal density across cortical depth using automated 3D analysis of confocal image stacks. Brain Struct Funct 222:3333-3353
Pesaran, Bijan; Freedman, David J (2016) Where Are Perceptual Decisions Made in the Brain? Trends Neurosci 39:642-644
Sherpa, Ang Doma; Xiao, Fanrong; Joseph, Neethu et al. (2016) Activation of ?-adrenergic receptors in rat visual cortex expands astrocytic processes and reduces extracellular space volume. Synapse 70:307-16

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