ADMINISTRATIVE CORE: This proposal describes the Administrative core for the Massachusetts Eye and Ear Infirmary (MEEI) P30 Center Core Grant for Vision Research. The purpose of the Administrative core is to 1) ensure equitable usage of the service cores;2) manage the P30 budget and resources;3) integrate core resources and coordinate activity among the core services;and 4) evaluate the core services and revise as user needs evolve. The administrative core is directed by the PI, Dr. Wiggs, with assistance from the resource core directors (Drs. Pierce and Pasquale), an Internal Advisory committee that includes the resource core directors and other senior staff, and an External Advisory Committee that includes the resource core directors as well as the Pis of the other two HMS P30s (Drs. Born and Zieske) and the PI of the MEEI NIDCD-funded P30 sCtpporting deafness research (Dr. Liberman).

Public Health Relevance

The adminstrative core for the Massachusetts Eye and Ear Infirmary P30 Center Core Grant for Vision Research will ensure that the P30 grant resources are effectively and efficiently used by the core vision scientists.

National Institute of Health (NIH)
Center Core Grants (P30)
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Study Section
Special Emphasis Panel (ZEY1)
Program Officer
Liberman, Ellen S
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Massachusetts Eye and Ear Infirmary
United States
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Loomis, Stephanie J; Kang, Jae H; Weinreb, Robert N et al. (2014) Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss. Ophthalmology 121:508-16
Yanai, Ryoji; Mulki, Lama; Hasegawa, Eiichi et al. (2014) Cytochrome P450-generated metabolites derived from ?-3 fatty acids attenuate neovascularization. Proc Natl Acad Sci U S A 111:9603-8
Wiggs, Janey L; Pawlyk, Basil; Connolly, Edward et al. (2014) Disruption of the blood-aqueous barrier and lens abnormalities in mice lacking lysyl oxidase-like 1 (LOXL1). Invest Ophthalmol Vis Sci 55:856-64
Hasegawa, Eiichi; Sweigard, Harry; Husain, Deeba et al. (2014) Characterization of a spontaneous retinal neovascular mouse model. PLoS One 9:e106507
Isayama, Tomoki; Chen, Ying; Kono, Masahiro et al. (2014) Coexpression of three opsins in cone photoreceptors of the salamander Ambystoma tigrinum. J Comp Neurol 522:2249-65
Matsumoto, H; Murakami, Y; Kataoka, K et al. (2014) Mammalian STE20-like kinase 2, not kinase 1, mediates photoreceptor cell death during retinal detachment. Cell Death Dis 5:e1269
Takeuchi, Kimio; Yanai, Ryoji; Kumase, Fumiaki et al. (2014) EGF-like-domain-7 is required for VEGF-induced Akt/ERK activation and vascular tube formation in an ex vivo angiogenesis assay. PLoS One 9:e91849
Kang, J H; Loomis, S J; Yaspan, B L et al. (2014) Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma. Eye (Lond) 28:662-71
Bailey, Jessica N Cooke; Yaspan, Brian L; Pasquale, Louis R et al. (2014) Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma. Hum Genet 133:1319-30
Matsumoto, Hidetaka; Kataoka, Keiko; Tsoka, Pavlina et al. (2014) Strain difference in photoreceptor cell death after retinal detachment in mice. Invest Ophthalmol Vis Sci 55:4165-74

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