The long-term objective of this application is to support current and future vision research endeavors at Indiana University, Bloomington. This infrastructure grant provides support for three shared resource modules: electronics, machine shop and scientific computing. The modules will expand the seamless integration of mechanical, electronics and software components in custom research equipment and new clinical technology, plus provide new coordination of activity across numerous inter-related laboratories and a sustained interaction with sophisticated supercomputing and 3D visualization resources on campus. The applications to our vision research projects are broad, including microscopic and ocular fluorimetry, cell physiology and molecular biology, advanced measurement and modeling of the optics of the eye. Novel imaging of the structures of the normal and pathological living human eye, studies of the normal and abnormal developing human visual system, and the development of new quantitative strategies to assess visual function in a clinical setting. The local research environment has expanded to include seven new active laboratories during the past eight years and at least three more are anticipated in the next three years.

Public Health Relevance

The proposed Core Grant supports the Research activities of the Indiana University Bloomington Vision Science community. This will support research ranging from control of development of eyes, to clinical applications of imaging and image formation in the eye.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY019008-03
Application #
8097993
Study Section
Special Emphasis Panel (ZEY1-VSN (08))
Program Officer
Liberman, Ellen S
Project Start
2009-07-01
Project End
2014-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
3
Fiscal Year
2011
Total Cost
$444,415
Indirect Cost
Name
Indiana University Bloomington
Department
Type
Schools of Optometry/Ophthalmol
DUNS #
006046700
City
Bloomington
State
IN
Country
United States
Zip Code
47401
Kurokawa, Kazuhiro; Liu, Zhuolin; Miller, Donald T (2017) Adaptive optics optical coherence tomography angiography for morphometric analysis of choriocapillaris [Invited]. Biomed Opt Express 8:1803-1822
Price, Derek A; Swanson, William H; Horner, Douglas G (2017) Using perimetric data to estimate ganglion cell loss for detecting progression of glaucoma: a comparison of models. Ophthalmic Physiol Opt 37:409-419
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Zhang, Wenlin; Li, Hongde; Ogando, Diego G et al. (2017) Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium. EBioMedicine 16:292-301
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Sawides, Lucie; de Castro, Alberto; Burns, Stephen A (2017) The organization of the cone photoreceptor mosaic measured in the living human retina. Vision Res 132:34-44
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King, Brett J; Sapoznik, Kaitlyn A; Elsner, Ann E et al. (2017) SD-OCT and Adaptive Optics Imaging of Outer Retinal Tubulation. Optom Vis Sci 94:411-422

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