The long-term objective of this application is to support current and future vision research endeavors at Indiana University, Bloomington. This infrastructure grant provides support for three shared resource modules: electronics, machine shop and scientific computing. The modules will expand the seamless integration of mechanical, electronics and software components in custom research equipment and new clinical technology, plus provide new coordination of activity across numerous inter-related laboratories and a sustained interaction with sophisticated supercomputing and 3D visualization resources on campus. The applications to our vision research projects are broad, including microscopic and ocular fluorimetry, cell physiology and molecular biology, advanced measurement and modeling of the optics of the eye. Novel imaging of the structures of the normal and pathological living human eye, studies of the normal and abnormal developing human visual system, and the development of new quantitative strategies to assess visual function in a clinical setting. The local research environment has expanded to include seven new active laboratories during the past eight years and at least three more are anticipated in the next three years.

Public Health Relevance

The proposed Core Grant supports the Research activities of the Indiana University Bloomington Vision Science community. This will support research ranging from control of development of eyes, to clinical applications of imaging and image formation in the eye.

National Institute of Health (NIH)
National Eye Institute (NEI)
Center Core Grants (P30)
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Study Section
Special Emphasis Panel (ZEY1-VSN (08))
Program Officer
Liberman, Ellen S
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Indiana University Bloomington
Schools of Optometry/Ophthalmol
United States
Zip Code
Chen, Angela M; Manh, Vivian; Candy, T Rowan (2018) Longitudinal Evaluation of Accommodation During Treatment for Unilateral Amblyopia. Invest Ophthalmol Vis Sci 59:2187-2196
Karst, Sonja G; Lammer, Jan; Radwan, Salma H et al. (2018) Characterization of In Vivo Retinal Lesions of Diabetic Retinopathy Using Adaptive Optics Scanning Laser Ophthalmoscopy. Int J Endocrinol 2018:7492946
Wu, Yifei; Thibos, Larry N; Candy, T Rowan (2018) Two-dimensional simulation of eccentric photorefraction images for ametropes: factors influencing the measurement. Ophthalmic Physiol Opt 38:432-446
Ashimatey, Bright S; King, Brett J; Swanson, William H (2018) Retinal putative glial alterations: implication for glaucoma care. Ophthalmic Physiol Opt 38:56-65
South, Fredrick A; Kurokawa, Kazuhiro; Liu, Zhuolin et al. (2018) Combined hardware and computational optical wavefront correction. Biomed Opt Express 9:2562-2574
Almutleb, Essam S; Bradley, Arthur; Jedlicka, Jason et al. (2018) Simulation of a central scotoma using contact lenses with an opaque centre. Ophthalmic Physiol Opt 38:76-87
Ashimatey, Bright S; King, Brett J; Malinovsky, Victor E et al. (2018) Novel Technique for Quantifying Retinal Nerve Fiber Bundle Abnormality in the Temporal Raphe. Optom Vis Sci 95:309-317
Ashimatey, Bright S; King, Brett J; Burns, Stephen A et al. (2018) Evaluating glaucomatous abnormality in peripapillary optical coherence tomography enface visualisation of the retinal nerve fibre layer reflectance. Ophthalmic Physiol Opt 38:376-388
Seemiller, Eric S; Cumming, Bruce G; Candy, T Rowan (2018) Human infants can generate vergence responses to retinal disparity by 5 to 10 weeks of age. J Vis 18:17
Sapoznik, Kaitlyn A; Luo, Ting; de Castro, Alberto et al. (2018) Enhanced retinal vasculature imaging with a rapidly configurable aperture. Biomed Opt Express 9:1323-1333

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