The purpose of the Experimental Design, Biostatistics, and Data Services (EBD) Core is to provide centralized research and statistical design, data analysis, and data management services to research supported by the Center for Alaska Native Health Research (CANHR). The EBD Core must address three issues that arise because CANHR work is based in community-based participatory research (CBPR) models and in Alaska Native settings. Research conducted by CANHR scientists is characterized by (1) qualitative as well as quantitative research designs, (2) analyses that often involve small sample longitudinal studies, and (3) research that is responsive to our CBPR partners. Community partners have expressed strong support for collaborative development of intervention studies addressing ongoing Alaska Native health issues of importance to them and that form the thematic disease focus of CANHR. Within the area of experimental and statistical design, the EBD Core will provide consultation to CANHR investigators proposing basic, applied, and intervention research projects. In addition, this work includes cross-cultural adaptation and development of measurement instruments, interview protocols, and designs for qualitative studies. The EBD Core will provide intensive consultation on statistical and qualitative analysis for CANHR research projects. These services will include both design and implementation of statistical analyses. Finally, the EBD Core will provide crucial data management services. These will include ongoing maintenance of several existing CANHR project databases, development of new databases to support future projects, and data access and reporting services. The EBD Core has the following three specific aims:
Specific Aim 1. Support the design of experimental, quasi-experimental, observational, and qualitative studies.
Specific Aim 2. Support the planning, development, and implementation of data analyses.
Specific Aim 3. Develop and maintain research databases.

Public Health Relevance

High quality experimental design, analytic, and data management services are crucial to the conduct of research conducted by CANHR. The EBD Core will provide these services to advance CANHR's CBPR model of collaborative inquiry with Alaska Native communities. These services will build capacity and sustain interdisciplinary CBPR and health disparities research projects to improve the health of Alaska Native people.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Center Core Grants (P30)
Project #
5P30GM103325-02
Application #
8545878
Study Section
Special Emphasis Panel (ZRR1-RI-B)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
2
Fiscal Year
2013
Total Cost
$232,370
Indirect Cost
$76,939
Name
University of Alaska Fairbanks
Department
Type
DUNS #
615245164
City
Fairbanks
State
AK
Country
United States
Zip Code
99775
Philip, Jacques; Ryman, Tove K; Hopkins, Scarlett E et al. (2017) Bi-cultural dynamics for risk and protective factors for cardiometabolic health in an Alaska Native (Yup'ik) population. PLoS One 12:e0183451
Sticka, Kendra D; Schnurr, Theresia M; Jerome, Scott P et al. (2017) Exercise Increases Glucose Transporter-4 Levels on Peripheral Blood Mononuclear Cells. Med Sci Sports Exerc :
Fohner, Alison E; Wang, Zhican; Yracheta, Joseph et al. (2016) Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup'ik Study Population from Southwestern Alaska. J Nutr 146:318-25
Philip, Jacques; Ford, Tara; Henry, David et al. (2016) Relationship of Social Network to Protective Factors in Suicide and Alcohol Use Disorder Intervention for Rural Yup'ik Alaska Native Youth. Interv Psicosoc 25:45-54
Lemas, Dominick J; Klimentidis, Yann C; Aslibekyan, Stella et al. (2016) Polymorphisms in stearoyl coa desaturase and sterol regulatory element binding protein interact with N-3 polyunsaturated fatty acid intake to modify associations with anthropometric variables and metabolic phenotypes in Yup'ik people. Mol Nutr Food Res 60:2642-2653
Ryman, Tove K; Boyer, Bert B; Hopkins, Scarlett et al. (2015) Characterising the reproducibility and reliability of dietary patterns among Yup'ik Alaska Native people. Br J Nutr 113:634-43
O'Brien, Diane M (2015) Stable Isotope Ratios as Biomarkers of Diet for Health Research. Annu Rev Nutr 35:565-94
Koller, Kathryn R; Metzger, Jesse S; Jolly, Stacey E et al. (2015) Cardiometabolic correlates of low type 2 diabetes incidence in western Alaska Native people - The WATCH study. Diabetes Res Clin Pract 108:423-31
Jolly, Stacey E; Koller, Kathryn R; Metzger, Jesse S et al. (2015) Prevalence of Hypertension and Associated Risk Factors in Western Alaska Native People: The Western Alaska Tribal Collaborative for Health (WATCH) Study. J Clin Hypertens (Greenwich) 17:812-8
Dubé, Joseph B; Wang, Jian; Cao, Henian et al. (2015) Common low-density lipoprotein receptor p.G116S variant has a large effect on plasma low-density lipoprotein cholesterol in circumpolar inuit populations. Circ Cardiovasc Genet 8:100-5

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