The Core Synthesis Facility was established in 2007 to provide state-of-the-art capabilities in synthetic organic chemistry to biomedical researchers in the State of North Dakota and beyond. The core has served a wide variety of research projects in multiple disciplines on the campus and throughout the region. Its services include equipment and expertise to conduct synthetic organic chemistry and providing access to small organic compounds, potential drug molecules, and labeled molecules for biomedical studies. The core has received institutional support by way of salary and benefit contributions of 50% for the manager. Dr. Yonghua Yang, as well as the COBRE Administrative Assistant who coordinates activities between the cores. The core is expected to be an important part of the growth and development of NDSU as a recruiting tool to attract new biomedical scientists, as a cost-effective measure to stretch federal research dollars, and as a means of teaching and training investigators in chemical techniques. Outreach to educational collectives has broadened the impact of the core on science in the region.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Center Core Grants (P30)
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Special Emphasis Panel (ZRR1-RI-B)
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North Dakota State University
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Wu, Jingjing; Zhu, Yingyue; Xue, Feng et al. (2014) Recent trends in SELEX technique and its application to food safety monitoring. Mikrochim Acta 181:479-491
Singh, Neha; Vasam, Goutham; Pawar, Rahul et al. (2014) Angiotensin-(1-7) reverses angiogenic dysfunction in corpus cavernosum by acting on the microvasculature and bone marrow-derived cells in diabetes. J Sex Med 11:2153-63
Dhillon, Harsharan; Chikara, Shireen; Reindl, Katie M (2014) Piperlongumine induces pancreatic cancer cell death by enhancing reactive oxygen species and DNA damage. Toxicol Rep 1:309-318
Zhang, Q; Padi, S K R; Tindall, D J et al. (2014) Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31. Cell Death Dis 5:e1486
Mahdi, Osama; Eklund, Bridget; Fisher, Nathan (2014) Laboratory culture and maintenance of Stenotrophomonas maltophilia. Curr Protoc Microbiol 32:Unit 6F.1.
Mei, Yang; Su, Minfei; Soni, Gaurav et al. (2014) Intrinsically disordered regions in autophagy proteins. Proteins 82:565-78
Su, Minfei; Mei, Yang; Sanishvili, Ruslan et al. (2014) Targeting ?-herpesvirus 68 Bcl-2-mediated down-regulation of autophagy. J Biol Chem 289:8029-40
Xu, Hui; Chen, Jiao; Birrenkott, Joseph et al. (2014) Gold-nanoparticle-decorated silica nanorods for sensitive visual detection of proteins. Anal Chem 86:7351-9
Mao, Xun; Gurung, Anant; Xu, Hui et al. (2014) Simultaneous detection of nucleic acid and protein using gold nanoparticles and lateral flow device. Anal Sci 30:637-42
Li, Bo; Liu, Qing; Xuan, Chengluan et al. (2013) GABAB receptor gene transfer into the nucleus tractus solitarii induces chronic blood pressure elevation in normotensive rats. Circ J 77:2558-66

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