The Admin-Mentoring Core will oversee administration of all fiscal and administrative operations of the third, transitional, cycle of the Cardiovascular COBRE. All budgets, for the scientific cores and the pilot programs, will be coordinated through the Admin Core as will all elements of recruitment, purchasing, and external support. This core will be responsible for interactions with the advisory committees and the NIH, will produce progress reports, will adjudicate any disputes over utilization of the scientific cores, and will assure compliance with all applicable agency regulations. In addition this Core will oversee the mentoring aspects of our COBRE. This will include supporting the training of young investigators, students at every level of training who work in the CCR, core personnel, and the scientists who use the Cores. It will also include the enhancement of a novel program of training of high school teachers in molecular biology, in order to help fill the pipeline of future biomedical workers in the State of Hawaii.
The Specific Aims of this Core are: 1. To provide efficient administration of all elements of the COBRE 2. To coordinate mentoring of those who provide and consume core services. 3. To supervise and expand an innovative, community-based, effort to train high school biology teachers in modern molecular biology.

Public Health Relevance

By providing efficient administrative support and coordinated mentoring of Core personnel, the Admin mentoring core will make the best use of program resources, provide required regulatory compliance, and allow our investigators to produce the best possible service and science. Our mentoring efforts will keep our cores at the cutting edge of modern biology and provide a highly leveraged approach to enhancing bioscience skills and understanding to the citizens of our State.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Center Core Grants (P30)
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Special Emphasis Panel (ZRR1-RI-B (01))
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University of Hawaii
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Lum, Corey J; Nakagawa, Kazuma; Shohet, Ralph V et al. (2017) The Cost-Benefit Balance of Statins in Hawai'i: A Moving Target. Hawaii J Med Public Health 76:99-102
Norton, Robert L; Fredericks, Gregory J; Huang, Zhi et al. (2017) Selenoprotein K regulation of palmitoylation and calpain cleavage of ASAP2 is required for efficient Fc?R-mediated phagocytosis. J Leukoc Biol 101:439-448
Dedinszki, Dóra; Szeri, Flóra; Kozák, Eszter et al. (2017) Oral administration of pyrophosphate inhibits connective tissue calcification. EMBO Mol Med 9:1463-1470
Pomozi, Viola; Brampton, Christopher; van de Wetering, Koen et al. (2017) Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice. Am J Pathol 187:1258-1272
Baumer, Yvonne; McCurdy, Sara; Alcala, Martin et al. (2017) CD98 regulates vascular smooth muscle cell proliferation in atherosclerosis. Atherosclerosis 256:105-114
Pomozi, Viola; Brampton, Christopher; Szeri, Flóra et al. (2017) Functional Rescue of ABCC6 Deficiency by 4-Phenylbutyrate Therapy Reduces Dystrophic Calcification in Abcc6(-/-) Mice. J Invest Dermatol 137:595-602
Lee, Amanda J; Polgar, Noemi; Napoli, Josephine A et al. (2016) Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep 6:31137
Chew, Glen M; Fujita, Tsuyoshi; Webb, Gabriela M et al. (2016) TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection. PLoS Pathog 12:e1005349
Pinto, Alexander R; Ilinykh, Alexei; Ivey, Malina J et al. (2016) Revisiting Cardiac Cellular Composition. Circ Res 118:400-9
Fong, Keith S K; Hufnagel, Robert B; Khadka, Vedbar S et al. (2016) A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure. Dis Model Mech 9:585-96

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