A COBRE Center dedicated to studying protein structure/function must have a means for producing a wide variety of proteins. The COBRE-PSF Protein Production Group (Core B) fulfills this role by serving the following functions. 1) It maintains a state-of-the-art facility for cloning, mutagenesis and protein production that is accessible to COBRE investigators, other Core Lab users, and PPG staff members. 2) It produces and delivers high quality proteins in a reliable and efficient manner on a fee-for-service basis. 3) It provides clients with expert advice and hands-on training in any or all of the strategies and techniques used the PPG Core Lab. The PPG staff consists of a Director, Dr. Philip Gao, and two experineced full time staff scientists. It is guided by a Steering committee comprised of three faculty researchers experienced in the art of protein production and characterization. During Phase III the PPG Core will transition from a pattern of support by COBRE plus user fees to one of basal support by the University plus user fees;this will ensure its long-term sustainability.

Public Health Relevance

The role ofthe Protein Production Group Core laboratory is to maintain a state-of-the-art laboratory for cloning, mutagenesis, protein expression and protein purification;to provide services in these areas for scientists investigating protein structure and function;and to provide training in the methods and techniques used in these activities.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Center Core Grants (P30)
Project #
1P30GM110761-01
Application #
8735420
Study Section
Special Emphasis Panel (ZGM1-TWD-C (C3))
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-06-30
Support Year
1
Fiscal Year
2014
Total Cost
$225,000
Indirect Cost
$75,000
Name
University of Kansas Lawrence
Department
Type
DUNS #
076248616
City
Lawrence
State
KS
Country
United States
Zip Code
66045