Abstract

The goals for the Tissue Culture and Monoclonal Antibody (TCMA) Laboratory remain as outlined in the original proposal for this Core facility: 1. To maintain a cost-effective centralized facility where cell culture and monoclonal antibody/hybridoma-related activities can be performed by and for investigators at the lawrence and the Medical Center settings of the MRDDRG. 2. To assist investigators in the growth and maintenance of primary cell cultures and cell lines used in a variety of molecular and cellular studies. 3. To carry out generation and characterization of monoclonal antibodies for MRDDRC investigators and maintain hybridoma cell lines for the investigators whose research programs require a consistent supply of antibodies. 4. To provide fluorescence activated flow cytometry capabilities for analysis of specific cell phenotypes and the effects of various experimental treatments.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
2P30HD002528-30
Application #
5212321
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
30
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Belousov, Andrei B; Nishimune, Hiroshi; Denisova, Janna V et al. (2018) A potential role for neuronal connexin 36 in the pathogenesis of amyotrophic lateral sclerosis. Neurosci Lett 666:1-4
Manzardo, A M; Weisensel, N; Ayala, S et al. (2018) Prader-Willi syndrome genetic subtypes and clinical neuropsychiatric diagnoses in residential care adults. Clin Genet 93:622-631
Moukarzel, Sara; Ozias, Marlies; Kerling, Elizabeth et al. (2018) Maternal Vitamin D Status and Infant Infection. Nutrients 10:
Chakrabarty, Anuradha; Liao, Zhaohui; Mu, Ying et al. (2018) Inflammatory Renin-Angiotensin System Disruption Attenuates Sensory Hyperinnervation and Mechanical Hypersensitivity in a Rat Model of Provoked Vestibulodynia. J Pain 19:264-277
Butler, Merlin G (2018) Pharmacogenetics and Psychiatric Care: A Review and Commentary. J Ment Health Clin Psychol 2:17-24
Bredin-Oja, Shelley L; Fielding, Heather; Fleming, Kandace K et al. (2018) Clinician vs. Machine: Estimating Vocalizations Rates in Young Children With Developmental Disorders. Am J Speech Lang Pathol 27:1066-1072
Butler, Merlin G; Hossain, Waheeda A; Tessman, Robert et al. (2018) Preliminary observations of mitochondrial dysfunction in Prader-Willi syndrome. Am J Med Genet A 176:2587-2594
McCarson, Kenneth E; Winter, Michelle K; Abrahamson, Dale R et al. (2018) Assessing complex movement behaviors in rodent models of neurological disorders. Neurobiol Learn Mem :
Mansour, Zaid M; Martin, Laura E; Lepping, Rebecca J et al. (2018) Brain Response to Non-Painful Mechanical Stimulus to Lumbar Spine. Brain Sci 8:
Loeb, Diane Frome; Imgrund, Caitlin M; Lee, Jaehoon et al. (2018) Preterm Neurodevelopmental Outcomes Following Orosensory Entrainment Intervention. J Neonatal Nurs 24:203-207

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