A2. JUSTIFICATION Dynamic Leadership: The primary function of the Administrative Core (ADM) is to provide strong consistent scientific leadership and to enunciate and execute a clear vision for the scientific direction of the Rose F. Kennedy IDDRC at Einstein. This will be achieved through active maintenance and constant re-evaluation of the six scientific Cores that provide the fundamental infrastructure of the center. The leadership will ensure prioritization of access to these Cores for IDDRC investigators, will consistently monitor Core utilization and cost-effectiveness, and ensure Core optimization and modernization through a system of continued evaluation and quality-control. The leadership will promote the activities and successes of the center and its investigators through dissemination of IDDRC work via our website, internal and external publications and dissemination through national media outlets. The leadership will coordinate and focus efforts around four identified thematic areas of IDD research strength. They will organize and manage a vibrant colloquium and mini-workshop series to promote investigator collaborations and community outreach. The leadership will administer a pilot grant program that will draw new investigators into the field of IDD research and provide seed funds for new innovative work from our established investigators. The Director, Dr. Walkley is an internationally recognized authority in IDD research with proven leadership skills and the requisite passion and determination to relentlessly advance and evolve the agenda of the IDDRC. He will take primary responsibility for executing this vision. He will consult with his associate director. Dr. Foxe, and leverage the collective expertise of his five key advisory committees to set a strong successful and vibrant agenda for the RFK-IDDRC. He will advocate at the highest levels of the college administration to guarantee the prominence of IDD research efforts at Einstein.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Center Core Grants (P30)
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Special Emphasis Panel (ZHD1-DSR-Y)
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Albert Einstein College of Medicine
United States
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Saied-Santiago, Kristian; Bülow, Hannes E (2018) Diverse roles for glycosaminoglycans in neural patterning. Dev Dyn 247:54-74
Wang, Ping; Zhao, Dejian; Lachman, Herbert M et al. (2018) Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons. Transl Psychiatry 8:13
Zhao, Yingjie; Guo, Tingwei; Fiksinski, Ania et al. (2018) Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects. Am J Med Genet A 176:2172-2181
Boudewyn, Lauren C; Walkley, Steven U (2018) Current concepts in the neuropathogenesis of mucolipidosis type IV. J Neurochem :
Wilson, Tommy J; Gray, Michael J; Van Klinken, Jan-Willem et al. (2018) Macronutrient composition of a morning meal and the maintenance of attention throughout the morning. Nutr Neurosci 21:729-743
Barnes, Jesse; Salas, Franklin; Mokhtari, Ryan et al. (2018) Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells. Mol Autism 9:44
Celestrin, Kevin; Díaz-Balzac, Carlos A; Tang, Leo T H et al. (2018) Four specific immunoglobulin domains in UNC-52/Perlecan function with NID-1/Nidogen during dendrite morphogenesis in Caenorhabditis elegans. Development 145:
Thomsen, Anna M; Gulinello, Maria E; Wen, Jing et al. (2018) Liposomal Cytarabine Induces Less Neurocognitive Dysfunction Than Intrathecal Methotrexate in an Animal Model. J Pediatr Hematol Oncol 40:e91-e96
Pera, Marta; Larrea, Delfina; Guardia-Laguarta, Cristina et al. (2017) Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease. EMBO J 36:3356-3371
Boudewyn, Lauren C; Sikora, Jakub; Kuchar, Ladislav et al. (2017) N-butyldeoxynojirimycin delays motor deficits, cerebellar microgliosis, and Purkinje cell loss in a mouse model of mucolipidosis type IV. Neurobiol Dis 105:257-270

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