The New York City-based HIV Center for Clinical and Behavioral Studies is dedicated to multidisciplinary research that will advance the implementation of the US National HIV/AIDS Strategy - to prevent new infections, improve health outcomes for people living with HIV, and reduce health disparities. In 2011, we are at a defining moment in the HIV epidemic with the emergence of effective biomedical approaches to HIV prevention. Yet, without rigorous behavioral and social science research to ensure uptake and adherence, these approaches will not realize their potential. In this renewal application, we propose important reconceptualizations and reconfigurations mobilizing a diverse and multidisciplinary cadre of senior scientists, early stage investigators, practitioners, and policy-makers from multiple academic, community and public health venues to (1) advance the science of HIV prevention, treatment, and care, providing the building blocks for combination prevention, (2) realize the full potential of biomedical HIV prevention and treatment strategies through the application of behavioral and social science theory and research, and (3) apply principles of implementation science to maximize our public health impact. We propose the following six Cores, reflecting our commitment to breaking new ground while building on documented strengths and accomplishments: (1) the Administrative Core to provide leadership that stimulates and manages innovative research through strategic planning, ensuring the highest scientific standards and ethical integrity, and efficient fiscal operations;(2) the Development Core to promote science innovation, provide internal peer review, and nurture early stage investigators;(3) the Intervention Science Core to provide expertise on intervention development and assessment, stimulate the integration of biomedical and behavioral approaches, and advise on the use of community-based participatory research methodologies;(4) the Statistics, Epidemiology and Data Management Core to provide a centralized resource for innovative research designs, statistical analysis, and data management;(5) the Public Health Practice and Policy Core to apply implementation science and ethical and policy analysis to close the gaps among science, public health practice, and policy;and (6) the New Media Core, to integrate new media and information technologies into HIV research and focus on these environments as areas in need of study. The HIV Center provides a rich, value-added resource to a large number of investigators, practitioners, and policy-makers, while attracting and training new investigators and making innovative, scientific, programmatic, and policy contributions that respond to the evolving HIV/AIDS epidemic on a national and international level.
New York City home to over a third of people living with HIV/AIDS in the US - has the highest number of new infections of any US city and large ethnic/racial minority populations coping with extreme economic and health disparities. From this US HIV epicenter, the HIV Center works in four continents to conduct leading research and build the capacity of scientists, advocates, practitioners, and policy-makers to decrease the impact of HIV/AIDS on individuals and communities. Our work will contribute to the actualization of the US National HIV/AIDS Strategy and provide public health practice models for the US and the world.
|Brown 3rd, William; Giguere, Rebecca; Sheinfil, Alan et al. (2018) Challenges and solutions implementing an SMS text message-based survey CASI and adherence reminders in an international biomedical HIV PrEP study (MTN 017). J Biomed Inform 80:78-86|
|Balán, Iván C; Frasca, Timothy; Dolezal, Curtis et al. (2018) HIV Risk Reduction by Avoiding Sex With Partners Unwilling to Undergo HIV Testing Is Not Coercion. J Acquir Immune Defic Syndr 78:e38|
|Kelvin, Elizabeth A; George, Gavin; Mwai, Eva et al. (2018) Offering self-administered oral HIV testing to truck drivers in Kenya to increase testing: a randomized controlled trial. AIDS Care 30:47-55|
|Benson, Stephanie; Elkington, Katherine S; Leu, Cheng-Shiun et al. (2018) Association Between Psychiatric Disorders, Substance Use, and Sexual Risk Behaviors in Perinatally HIV-Exposed Youth. J Assoc Nurses AIDS Care 29:538-549|
|Parcesepe, Angela M; Tymejczyk, Olga; Remien, Robert et al. (2018) Psychological distress, health and treatment-related factors among individuals initiating ART in Oromia, Ethiopia. AIDS Care 30:338-342|
|Balán, Iván C; Giguere, Rebecca; Brown 3rd, William et al. (2018) Brief Participant-Centered Convergence Interviews Integrate Self-Reports, Product Returns, and Pharmacokinetic Results to Improve Adherence Measurement in MTN-017. AIDS Behav 22:986-995|
|Barnes, David M; Des Jarlais, Don C; Wolff, Margaret et al. (2018) A qualitative study of persons who inject drugs but who have never helped others with first injections: how their views on helping contrast with the views of persons who have helped with first injections, and implications for interventions. Harm Reduct J 15:43|
|Iribarren, Sarah J; Ghazzawi, Alhasan; Sheinfil, Alan Z et al. (2018) Mixed-Method Evaluation of Social Media-Based Tools and Traditional Strategies to Recruit High-Risk and Hard-to-Reach Populations into an HIV Prevention Intervention Study. AIDS Behav 22:347-357|
|Masvawure, Tsitsi B; Mantell, Joanne E; Tocco, Jack Ume et al. (2018) Intentional and Unintentional Condom Breakage and Slippage in the Sexual Interactions of Female and Male Sex Workers and Clients in Mombasa, Kenya. AIDS Behav 22:637-648|
|Zhang, Yinfeng; Fogel, Jessica M; Guo, Xu et al. (2018) Antiretroviral drug use and HIV drug resistance among MSM and transgender women in sub-Saharan Africa. AIDS 32:1301-1306|
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