PROJECT 2. Personalized Interventions to Improve Treatment Engagement in BD: Jodi M. Gonzalez, Bren Manaugh (CHCS), Charles Bowden, Jim Mintz A. What we propose to do: This project will assess the effectiveness of a personalized peer to peer intervention (PPI) compared with a control condition in persons with BD who have low treatment engagement. We believe that a significant contributor to worse outcomes in Hispanic BD patients is that culturally induced stigmatization of mental illness serves as a barrier that prevents patients from adequate engagement in treatment. To study this issue we propose using a peer to peer intervention. We believe that this interaction will enhance a sense of connectedness which will improve understanding of health care programs, increase sense of empowerment and engagement and consequently wellness.
PPI aims to personalize psychosocial evidence based interventions through targeting the needs of individual with low treatment engagement. Figure 1 provides a conceptual rationale. Outcomes will be assessed by adherence to psychiatric visits and medication(s), quality of alliance with the provider/system and symptomatic and functional measures.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH086045-02
Application #
8381450
Study Section
Special Emphasis Panel (ZMH1-ERB-F)
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
2
Fiscal Year
2012
Total Cost
$112,028
Indirect Cost
$25,653
Name
University of Texas Health Science Center San Antonio
Department
Type
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Fries, Gabriel R; Colpo, Gabriela D; Monroy-Jaramillo, Nancy et al. (2017) Distinct lithium-induced gene expression effects in lymphoblastoid cell lines from patients with bipolar disorder. Eur Neuropsychopharmacol 27:1110-1119
Tohen, Mauricio; Mintz, Jim; Bowden, Charles L (2016) Analysis of bipolar maintenance treatment with lithium versus olanzapine utilizing Multi-state Outcome Analysis of Treatments (MOAT). Bipolar Disord 18:282-7
Perlick, Deborah A; Berk, Lesley; Kaczynski, Richard et al. (2016) Caregiver burden as a predictor of depression among family and friends who provide care for persons with bipolar disorder. Bipolar Disord 18:183-91
Bowden, C L; Mintz, J; Tohen, M (2016) Multi-state outcome analysis of treatments (MOAT): application of a new approach to evaluate outcomes in longitudinal studies of bipolar disorder. Mol Psychiatry 21:237-42
Bowden, Charles L; Singh, Vivek (2016) The use of antidepressants in bipolar disorder patients with depression. Expert Opin Pharmacother 17:17-25
Arnold, Jodi Gonzalez; Martinez, Cervando; Zavala, Juan et al. (2016) Investigating symptom domains of bipolar disorder for Spanish-speakers using the Bipolar Inventory of Symptoms Scale. J Affect Disord 205:239-244
Gonzalez Arnold, Jodi; Salcedo, Stephanie; Ketter, Terrence A et al. (2015) An exploratory study of responses to low-dose lithium in African Americans and Hispanics. J Affect Disord 178:224-8
Bowden, Charles L (2015) Providing assessable information on effectiveness of maintenance treatments for bipolar disorder to psychiatrists and patients. Evid Based Ment Health 18:58
Singh, V; Bowden, C L; Gonzalez, J M et al. (2013) Discriminating primary clinical states in bipolar disorder with a comprehensive symptom scale. Acta Psychiatr Scand 127:145-52
Perlick, D A; Gonzalez, J; Michael, L et al. (2012) Rumination, gender, and depressive symptoms associated with caregiving strain in bipolar disorder. Acta Psychiatr Scand 126:356-62

Showing the most recent 10 out of 12 publications