Abstract

The Collaboration and Service efforts at the National Center for the Quantitative Biology of Complex Systems (NCQBCS) will be focused on the dissemination of expertise and knowledge to researchers across the country, establishing a strong foothold for our developed technologies throughout the nation. A core mission of the NCQBCS is to provide broad access to proteomic technologies, facilitating the advancement of biomedical research programs at institutions that lack the skills and/or resources necessary to conduct proteomic experiments. Our Center's effective blend of technological expertise and state-of-the-art instrumentation makes us well-suited and excited to work with these outside investigators towards a unified goal. Having formed and managed numerous productive and successful collaborations in the past, we look forward to establishing the NCQBCS as a valuable resource that will provide Collaboration and Service opportunities to the biomedical research community.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Biotechnology Resource Grants (P41)
Project #
5P41GM108538-03
Application #
9517086
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
3
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715

  Publications

Hutchins, Paul D; Russell, Jason D; Coon, Joshua J (2018) LipiDex: An Integrated Software Package for High-Confidence Lipid Identification. Cell Syst 6:621-625.e5
Jha, Pooja; McDevitt, Molly T; Gupta, Rahul et al. (2018) Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species. Cell Syst 6:722-733.e6
Hebert, Alexander S; Prasad, Satendra; Belford, Michael W et al. (2018) Comprehensive Single-Shot Proteomics with FAIMS on a Hybrid Orbitrap Mass Spectrometer. Anal Chem 90:9529-9537
Mitok, Kelly A; Freiberger, Elyse C; Schueler, Kathryn L et al. (2018) Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion. J Biol Chem 293:5860-5877
Lee, Ji-Hoon; Mand, Michael R; Kao, Chung-Hsuan et al. (2018) ATM directs DNA damage responses and proteostasis via genetically separable pathways. Sci Signal 11:
Rhoads, Timothy W; Burhans, Maggie S; Chen, Vincent B et al. (2018) Caloric Restriction Engages Hepatic RNA Processing Mechanisms in Rhesus Monkeys. Cell Metab 27:677-688.e5
Chen, Zhengwei; Yu, Qing; Hao, Ling et al. (2018) Site-specific characterization and quantitation of N-glycopeptides in PKM2 knockout breast cancer cells using DiLeu isobaric tags enabled by electron-transfer/higher-energy collision dissociation (EThcD). Analyst 143:2508-2519
Jiang, Xiaoyue; Xiang, Feng; Jia, Chenxi et al. (2018) Relative Quantitation of Neuropeptides at Multiple Developmental Stages of the American Lobster Using N, N-Dimethyl Leucine Isobaric Tandem Mass Tags. ACS Chem Neurosci 9:2054-2063
Lapointe, Christopher P; Stefely, Jonathan A; Jochem, Adam et al. (2018) Multi-omics Reveal Specific Targets of the RNA-Binding Protein Puf3p and Its Orchestration of Mitochondrial Biogenesis. Cell Syst 6:125-135.e6
Overmyer, Katherine A; Tyanova, Stefka; Hebert, Alex S et al. (2018) Multiplexed proteome analysis with neutron-encoded stable isotope labeling in cells and mice. Nat Protoc 13:293-306

Showing the most recent 10 out of 32 publications