The RTC will enable the CU Center to address issues of high relevance, maximize program investments, and foster innovation while promoting cutting-edge research on the health impacts and geochemistry of Arsenic (As) and Manganese (Mn) via drinking water primarily from groundwater. Our emphasis is on government partnerships, including EPA, ATSDR and local/state agencies managing groundwater drinking water supplies. RTC will work with each Project PI and the Community Engagement Core (CEC) to engage in constructive collaborations with agencies that can benefit from our expertise. The RTC will facilitate interactions with site managers of the Vineland Superfund (SF) site (i.e., EPA, USACE, NJDEP) where CU scientists will work on applying accelerated remediation approaches. With NJDEP, NJGS, USGS and local county DOH partners, we will produce a proof of concept for 3-D risk based maps of As for sitting private wells and create educational videos for residents with arsenic in their wells. The RTC and GIS partners at EPA, ATSDR, and IH will develop and utilize state-of-the art geospatial and analytical tools. Updates to CU SRP online mapping service will identify and analyze the impacts of SF sites on vulnerable populations, to more effectively remediate high priority sites. We will communicate novel findings from our biomedical research to broad audiences via organized forums in the US and Bangladesh. Research translation will be augmented by monthly multidisciplinary seminars, information exchange forums, and targeted meetings. Our EPA partners will announce selected CU SRP seminars via TechDirect (with 37,000+ subscribers) and broadcast them via the online CLU-IN service. We will increase our collaborations with other Centers and SF agencies in planning the SRP Annual Meeting, RTC workshops, Partnership for Environmental Public Health, and other EPA, NIEHS, and ATSDR events. We will inform NIEHS of our Center's research briefs, publications, and success stories on a regular basis via phone, emails, and the online SRP data form. Our own website will be updated on an ongoing basis, profiling CU research &scientists and linking to key resources from EPA, NIEHS, SRP websites and to local issues of interest to the general public.
Research translation can augment and accelerate the impact of basic and applied science on public policies, regulations, and human behavior thereby providing greater protection to the public from adverse exposures to As and Mn in drinking water.
|McClintock, Tyler R; Parvez, Faruque; Wu, Fen et al. (2016) Major dietary patterns and carotid intima-media thickness in Bangladesh. Public Health Nutr 19:218-29|
|Sun, Jing; Bostick, Benjamin C; Mailloux, Brian J et al. (2016) Effect of oxalic acid treatment on sediment arsenic concentrations and lability under reducing conditions. J Hazard Mater 311:125-33|
|Flanagan, Sara V; Spayd, Steven E; Procopio, Nicholas A et al. (2016) Arsenic in private well water part 2 of 3: Who benefits the most from traditional testing promotion? Sci Total Environ 562:1010-8|
|Khan, Mahfuzur R; Koneshloo, Mohammad; Knappett, Peter S K et al. (2016) Megacity pumping and preferential flow threaten groundwater quality. Nat Commun 7:12833|
|Howe, Caitlin G; Liu, Xinhua; Hall, Megan N et al. (2016) Sex-specific associations between one-carbon metabolism indices and posttranslational histone modifications in arsenic-exposed Bangladeshi adults. Cancer Epidemiol Biomarkers Prev :|
|Newman, Jonathan D; Navas-Acien, Ana; Kuo, Chin-Chi et al. (2016) Peripheral Arterial Disease and Its Association With Arsenic Exposure and Metabolism in the Strong Heart Study. Am J Epidemiol 184:806-817|
|Wasserman, Gail A; Liu, Xinhua; Parvez, Faruque et al. (2016) Child Intelligence and Reductions in Water Arsenic and Manganese: A Two-Year Follow-up Study in Bangladesh. Environ Health Perspect 124:1114-20|
|Sanchez, Tiffany R; Perzanowski, Matthew; Graziano, Joseph H (2016) Inorganic arsenic and respiratory health, from early life exposure to sex-specific effects: A systematic review. Environ Res 147:537-55|
|Liu, Xinhua; Jin, Zhezhen; Graziano, Joseph H (2016) Comparing paired biomarkers in predicting quantitative health outcome subject to random censoring. Stat Methods Med Res 25:447-57|
|Sun, Jing; Chillrud, Steven N; Mailloux, Brian J et al. (2016) Enhanced and stabilized arsenic retention in microcosms through the microbial oxidation of ferrous iron by nitrate. Chemosphere 144:1106-15|
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