The PRoTECT (Puerto Rico Testsite for Exploring Contamination Threats) Program includes five research projects, supported by two research support cores that will be conducted by a cross-disciplinary, multiuniversity team. The Administrative Core aims to (1) provide Program leadership and coordination;(2) facilitate and ensure integration of cross-disciplinary, multi-university activities;(3) provide fiscal management and administrative services and monitor resources and expenditures;(4) maintain smooth interaction with external advisory committee members and active communication with the NIEHS, EPA and SBRP program;(5) provide program documentation, reporting and assessment;and (6) promote Program activities among the participating institutions, government and industry. Achieving these aims while managing geographically distributed multi-university teams will require a sophisticated administrative structure. The initial decisions and plans, together with an effective communication structure, are crucial to maintaining active collaboration and coordination among researchers and institutions. Information Technology communication systems will support PRoTECT's cross-disciplinary, multi-university research and administration activities. Committees have also been formed to advise, coordinate and assess the effort with the Program Directors. These include an Executive Committee (to manage, facilitate and monitor the technical quality of the projects/cores), an Institutional Partnership Committee (to provide the necessary institutional-level guidance and promote the long-range strategic goals), a Scientific Advisory Committee (to assess research merit, cross-disciplinary integration, translation and relevance of projects, cores, and program), a Research Translation Committee and a Training Advisory Committee. Frequent and routine meetings and interaction will be planned and calendar dates will be established for these events. In addition to training activities and specific project/core interactions, the following specific key PRoTECT events will be adopted to ensure cross-disciplinary interaction: (1) monthly cross-disciplinary multi-university """"""""Town"""""""" meetings: (2) webinars and (3) an annual PRoTECT conference. The Executive Committee will oversee program documentation and assessment. The Committee will utilize the annual conference for direct interactions between the participants and committees, and for assessment of program activities.

Public Health Relevance

The Administrative Core is a required component to provide leadership and guidance in fulfilling the goals of the program. The Administrative Core is required to provide an infrastructure that promotes cross disciplinary interaction, research integration, research planning and coordination, fiscal oversight and resource management.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
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Special Emphasis Panel (ZES1-LWJ-M)
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Northeastern University
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Ferguson, Kelly K; Colacino, Justin A; Lewis, Ryan C et al. (2017) Personal care product use among adults in NHANES: associations between urinary phthalate metabolites and phenols and use of mouthwash and sunscreen. J Expo Sci Environ Epidemiol 27:326-332
Elkin, Elana R; O'Neill, Marie S (2017) Trends in Environmental Tobacco Smoke (ETS) Exposure and Preterm Birth: Use of Smoking Bans and Direct ETS Exposure Assessments in Study Designs. Chem Res Toxicol 30:1376-1383
Ferguson, Kelly K; McElrath, Thomas F; Pace, Gerry G et al. (2017) Urinary Polycyclic Aromatic Hydrocarbon Metabolite Associations with Biomarkers of Inflammation, Angiogenesis, and Oxidative Stress in Pregnant Women. Environ Sci Technol 51:4652-4660
Park, Hae-Ryung; Harris, Sean M; Boldenow, Erica et al. (2017) Group B Streptococcus Activates Transcriptomic Pathways Related to Premature Birth in Human Extraplacental Membranes In Vitro. Biol Reprod :
Ferguson, Kelly K; Meeker, John D; Cantonwine, David E et al. (2017) Environmental phenol associations with ultrasound and delivery measures of fetal growth. Environ Int 112:243-250
Shao, Gang; Agar, Jeffrey; Giese, Roger W (2017) Cold-induced aqueous acetonitrile phase separation: A salt-free way to begin quick, easy, cheap, effective, rugged, safe. J Chromatogr A 1506:128-133
Wang, Poguang; Giese, Roger W (2017) Recommendations for quantitative analysis of small molecules by matrix-assisted laser desorption ionization mass spectrometry. J Chromatogr A 1486:35-41
Ferguson, Kelly K; Chen, Yin-Hsiu; VanderWeele, Tyler J et al. (2017) Mediation of the Relationship between Maternal Phthalate Exposure and Preterm Birth by Oxidative Stress with Repeated Measurements across Pregnancy. Environ Health Perspect 125:488-494
Aung, Max T; Johns, Lauren E; Ferguson, Kelly K et al. (2017) Thyroid hormone parameters during pregnancy in relation to urinary bisphenol A concentrations: A repeated measures study. Environ Int 104:33-40
Yuan, Ye; Meeker, John D; Ferguson, Kelly K (2017) Serum polybrominated diphenyl ether (PBDE) concentrations in relation to biomarkers of oxidative stress and inflammation: The National Health and Nutrition Examination Survey 2003-2004. Sci Total Environ 575:400-405

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