Abstract

The Data Management and Modeling Core (DMMC) will provide for the efficient collection, cleaning and effective management of the biomedical, xenobiotic, demographic and environmental data being collected and analyzed across the PRoTECT project. This core will also provide support for environment contamination fate and transport modeling, GIS support, multi-dimensional data mining and visualization and programming expertise to build customized user interfaces that allow for efficient and accurate data entry and data analysis. A key feature will be to provide all of these services via the Internet to support the distributed university model present within the PRoTECT project. The DMMC will allow for the effective dissemination of GIS-based data presentation and support both modeling and data analysis tools developed or purchased to support the research efforts in this Program.

Public Health Relevance

The PRoTECT Data Management and Modeling Core will provide database, GIS, modeling and analysis capabilities to teams of engineers and scientists that are studying soil and groundwater contamination, specifically Superfund contamination, and their effect on the preterm birth rate.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES017198-03
Application #
8375207
Study Section
Special Emphasis Panel (ZES1-LWJ-M)
Project Start
Project End
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
3
Fiscal Year
2012
Total Cost
$214,087
Indirect Cost
$86,444

  Institution

Name
Northeastern University
Department
Type
DUNS #
001423631
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Elkin, Elana R; Harris, Sean M; Loch-Caruso, Rita (2018) Trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line. Toxicol Appl Pharmacol 338:30-42
Aker, Amira M; Johns, Lauren; McElrath, Thomas F et al. (2018) Associations between maternal phenol and paraben urinary biomarkers and maternal hormones during pregnancy: A repeated measures study. Environ Int 113:341-349
Xue, Yunfei; Rajic, Ljiljana; Chen, Long et al. (2018) Electrolytic control of hydrogen peroxide release from calcium peroxide in aqueous solution. Electrochem commun 93:81-85
Taqieddin, Amir; Allshouse, Michael R; Alshawabkeh, Akram N (2018) Review-Mathematical Formulations of Electrochemically Gas-Evolving Systems. J Electrochem Soc 165:E694-E711
Yu, Xue; Feric, Zlatan; Cordero, José F et al. (2018) Potential influence of temperature and precipitation on preterm birth rate in Puerto Rico. Sci Rep 8:16106
Koman, Patricia D; Hogan, Kelly A; Sampson, Natalie et al. (2018) Examining Joint Effects of Air Pollution Exposure and Social Determinants of Health in Defining ""At-Risk"" Populations Under the Clean Air Act: Susceptibility of Pregnant Women to Hypertensive Disorders of Pregnancy. World Med Health Policy 10:7-54
Park, Hae-Ryung; Harris, Sean M; Boldenow, Erica et al. (2018) Group B streptococcus activates transcriptomic pathways related to premature birth in human extraplacental membranes in vitro. Biol Reprod 98:396-407
Torres, Norma I; Yu, Xue; Padilla, Ingrid Y et al. (2018) The influence of hydrogeological and anthropogenic variables on phthalate contamination in eogenetic karst groundwater systems. Environ Pollut 237:298-307
Ferguson, Kelly K; Yu, Youfei; Cantonwine, David E et al. (2018) Foetal ultrasound measurement imputations based on growth curves versus multiple imputation chained equation (MICE). Paediatr Perinat Epidemiol 32:469-473
Boss, Jonathan; Zhai, Jingyi; Aung, Max T et al. (2018) Associations between mixtures of urinary phthalate metabolites with gestational age at delivery: a time to event analysis using summative phthalate risk scores. Environ Health 17:56

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