This application proposes a second five-year follow-up evaluation of a sample of 338 ethnically diverse, young adults (males=148) between the ages of 24-29 years old to examine the 'Deviance Prone' model of vulnerability in relation to predicting several alcohol use behaviors, including pathological involvement. This model posits that a significant aspect of the susceptibility for developing pathological alcohol involvement due to a parental history of alcoholism may result from deficient socialization and problem behavior. Although the Deviance Prone model was originally proposed as a heuristic model to explain the development of pathological alcohol involvement, many elements of the model have also been implicated as predictors of early onset of alcohol use and early heavy use of alcohol. The proposed study builds upon and extends our previous work on conduct problems and antisocial personality disorder with this and other samples. Information on key features of the model were initially collected when subjects were 14-19 years old and again at 19-24 years old. The study is unique in that the sample was ascertained from the community, is ethnically diverse, and has been well characterized using clinical, psychosocial, cognitive, and electrophysiological measures during the two initial assessments; parents were also directly interviewed. Using data from the three different time points, the present proposal will: 1) test the accuracy of the model for predicting different drinking behaviors at three different points in the subjects' lives: in mid-adolescence, in late adolescence, and in young adulthood; 2) examine the influence of age, ethnicity, gender, peer, and family relations, and coping ability as potential mediators/moderators of the Deviance Prone model's ability to predict alcohol use and alcohol problems at these three different time points; and 3) examine the accuracy of the Deviance Prone model for predicting alcohol use behaviors over time. Using structural equation modeling methods, the data collected at baseline and at Time 2 will be used to predict drinking behaviors, including pathological alcohol use, at Time 3. We will also continue our analyses using the baseline data to predict alcohol use behaviors at Time 2. The stability and efficiency of the Deviance Prone model for predicting early initiation of regular alcohol use, heavy regular use, and pathological alcohol involvement at these three different points in time will also be examined.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Specialized Center (P50)
Project #
5P50AA003510-29
Application #
7552536
Study Section
Special Emphasis Panel (ZAA1)
Project Start
Project End
Budget Start
2005-12-01
Budget End
2006-11-30
Support Year
29
Fiscal Year
2006
Total Cost
$318,275
Indirect Cost
Name
University of Connecticut
Department
Type
DUNS #
022254226
City
Farmington
State
CT
Country
United States
Zip Code
06030
Rash, Carla J; Alessi, Sheila M; Petry, Nancy M (2017) Substance Abuse Treatment Patients in Housing Programs Respond to Contingency Management Interventions. J Subst Abuse Treat 72:97-102
Howland, Maryhope; Armeli, Stephen; Feinn, Richard et al. (2017) Daily emotional stress reactivity in emerging adulthood: temporal stability and its predictors. Anxiety Stress Coping 30:121-132
Rash, Carla J; Petry, Nancy M (2016) Gambling Disorder in the DSM-5: Opportunities to Improve Diagnosis and Treatment Especially in Substance Use and Homeless Populations. Curr Addict Rep 3:249-253
Lieberman, Richard; Armeli, Stephen; Scott, Denise M et al. (2016) FKBP5 genotype interacts with early life trauma to predict heavy drinking in college students. Am J Med Genet B Neuropsychiatr Genet 171:879-87
Meredith, Steven E; Alessi, Sheila M; Petry, Nancy M (2015) Smartphone applications to reduce alcohol consumption and help patients with alcohol use disorder: a state-of-the-art review. Adv Health Care Technol 1:47-54
Armeli, Stephen; Sullivan, Tami P; Tennen, Howard (2015) Drinking to Cope Motivation as a Prospective Predictor of Negative Affect. J Stud Alcohol Drugs 76:578-84
Ohannessian, Christine McCauley; Finan, Laura J; Schulz, Jessica et al. (2015) A Long-Term Longitudinal Examination of the Effect of Early Onset of Alcohol and Drug Use on Later Alcohol Abuse. Subst Abus 36:440-4
O'Hara, Ross E; Armeli, Stephen; Tennen, Howard (2014) College students' daily-level reasons for not drinking. Drug Alcohol Rev 33:412-9
Sun, Jiangwen; Bi, Jinbo; Kranzler, Henry R (2014) Multiview comodeling to improve subtyping and genetic association of complex diseases. IEEE J Biomed Health Inform 18:548-54
Bi, Jinbo; Gelernter, Joel; Sun, Jiangwen et al. (2014) Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis. Am J Med Genet B Neuropsychiatr Genet 165B:148-56

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